8 Salisbury, 



ing to the temperament and constitution and state of health of 

 the patient; the irritation assumes a clironic form and the suft'er- 

 ings gradually grow less and less till they disappear. In irri- 

 table sensative constitutions, — the irritation in the fauces, larynx, 

 pharynx and bronchii — become so great that the parts spasmo- 

 dically close in attempts to swallow, — or to inhale air charged 

 with anything which excites the inflamed parts. I have no doubt 

 from what I have seen but that death may have occasionally 

 occurred in the acute stage of this disease, from spasms of the 

 pharynx and epiglottis. 



Secretion. The cells of the mucus, first secreted from 

 the surfaces invaded, are large round mucous cells, not differing 

 materially from those in health. Soon however, they begin to be 

 shrunken and jagged and in a few days they asume, many of 

 them, — the appearance and characters of pus cells (muco-pus). 

 The amount of secretion discharged from the air passages at any 

 one time is small; yet the presence of this small quantity creates 

 so much irritation, that it is very difficult, — during the acute 

 stage of the attack, — to keep, for any length of time from 

 coughing and sneezing. The secretion is thin, clear and watery 

 at first and small in quantity, — soon becoming thicker and more 

 turbid. The cough is short and somewhat painful and the in- 

 vaded surfaces feel irritated, raw and hot. The cough raises but 

 a small quantity at each time, and relieves the irritation and itch- 

 ing but for a few moments. 



Whenever the parasites are developing rapidly on the velum 

 palati, — most intense paroxysms of coughing are excited, which 

 are long and persistant and painful and sometimes are accom- 

 panied by severe spasms of the epiglottis. Often an irritation 

 and itching will be felt, on one side of the throat only, — ex- 

 citing constant desire to cough. In such cases the irritation will 

 always be on the side on which the nasal passage is closed. Un- 

 der such circumstances, inhaling remedies through the mouth very 

 often fails to check the coughing for but a few moments only. 

 By clearing the closed up nasal passage, and inhaling through it, 

 — the coughing and irritation is soon checked. The reason of 

 this is, — that the parasites are developing rapidly on the poste- 

 rior surface of the wing of the palate on the side of the nasal 

 stoppage; and are constantly working down into the larynx and 

 pharynx on that side. 



