20 Hallier, 
membranes presented no marked alteration. The various states 
of congestion and ulceration in the alimentary canal offered no 
revelations of interest to microscopical study. 
5) The muscular system presented a darker coloration than in 
healthy animals, but under the microscope revealed no alteration 
in structure. 
6) The nervous system was entirely free from discoloration 
or structural change. 
7) The adipose and areolar tissues were tinged by a diffused 
yellow coloration. Occasional yellow flakes were found in them. 
and about the kidney circumscribed extravasations of blood. Beau- 
tiful crystals of haematoidine were found in old extravasations. 
8) The lungs were remarkably free from acute disease. 
Part Second. 
Conclusions in regard to the pathological nature of the disease. 
‘To sum up the results of microscopical investigation, and 
give the pathological conclusions to which they point, the Texas 
Cattle Disease is an acute, infectious, febrile disorder, attended 
by morbid action of the liver, its mest distinctive phenomena 
being explicable as the results of the hepatic affection. The dis- 
solution of the coloring matter of the blood corpuscles in the 
liquor sanguinis, and the haematuria are consequent upon the en- 
trance of bile into the blood-vessels in whatever manner effected. 
In the experiments of Kuhne and Frerichs, the injection of bile, 
or of its salts, into the blood, was followed in the great majority 
of their experiments, upon the lower animals, by the appearance 
of blood in the urine. The solvent action of the bile upon the 
blood corpuscles, and the consequent liberation of their coloring 
matter can be readily witnessed under the microscope, each disc 
disappearing suddenly, like a light blown out, and the liquid as- 
suming an orange tint. The blood thus altered in character be- 
comes liable to extravasation, other haemorrhages than haema- 
turia being frequent attendants upon attacks of jaundice. 
That bile is mingled with the blood is proved by the. yellow 
color of the serum, its yellow flocculi, its crystals of cholesterine, 
by the yellow drops in the epithelium of the tubuli uriniferi, by 
the yellow granules in the spleen and by the haematuria. These 
results cannot follow the mere accumulation in the blood of the 
constituent elements of bile; the proximate principles of the bile 
