22 Hallier, 
than de blood or the bile itself. A magnifying power of over one 
thousand diameters and a lens of good penetrating power were 
necessary to their definition. Within a few hours of removal 
from the body, numerous cryptococcus (or torula) cells, resulting 
from the development of the former, were found, often containing 
crimson granules, as represented in Fig. 6 Plate 10. Specimens 
of bile and blood were collected from healthy animals and carefully 
examined, but in no instance did the forms described make their 
appearance. The ordinary attendants on putrefaction were alone de- 
scribed. Whether these forms of micrococcus and cryptococcus 
were merely accidental and attendant on a process of fermentation 
taking place in the bile, or were peculiar to the disease, their pre- 
sence was an interesting fact, and their nature deserving of careful 
investigation. Their development was accordingly studied under 
various conditions. They were planted in solutions of sugar, gum 
and saliva, which had been boiled in order to destroy whatever 
germs of a different nature the solutions might contain, and were 
kept hermetically sealed at a temperature of 100° Fahrenheit for 
several days. The resulting anaerophytic forms (cryptococcus and 
torula Fig. 4 Plate 10) were planted on slices of apple etc., and their 
development was noted, as represented in Plate 10. After a pe- 
riod of two weeks the planted area was found covered with peni- 
cillium, as represented in Plate No. 12*), while de rest of the 
surface was free from vegetable growth. At the same time 
cryptococcus guttulatus, from the intestine of a rabbit which 
had been fed on the morbid bile, was also planted on slices of 
apple, and the germination represented in Plate No. 11 noted. 
This was done for the purpose of comparison merely, crypto- 
coccus from the bile, however, manifested very different pheno- 
mena, although under precisely similar conditions with the for- 
mer. After two weeks it had merely increased in quantity, ag- 
gregations of spores having been formed visible to the naked eye, 
but no filaments.“ 
Herr Professor Stiles giebt nun eine kurze Besprechung 
meiner Ansicht von den reifen und nicht reifenden Formen der 
Pilze und fährt fort: 
„I have taken warning from the numerous disappointments 
*) Muss heissen Plate No. 13, Anm, d. Red, 
