90 DR. J. W. JENKINSON ON THE [Feb. 6, 



those of acid hfematoporphyrin ai-e seen ; the violet end is also 

 cut off. 



" This pigment seems evidently to be identical with the banded 

 one obtained from the Sheep. 



" It is to be noted that none of the solutions in the case of 

 either the Sheep or Cow was coloured the deep red chai'acteiistic 

 of hjematoporphyi-in. This was probably due (a) to the small 

 amount of the hjematoporphyrin-like pigment present, and (/3) to 

 impurities." 



From this report of Dr. McMunn's it seems quite clear that two 

 distinct pigments are present in the Ungulate placenta: (1) a 

 pigment soluble in alcohol, ether, and chloroform, which shows no 

 bands, but absorbs a little of the violet end of the spectrum ; (2) a 

 pigment soluble in the same three media, but giving in neutral 

 solution two bands very nearly but not quite in the position of 

 the bands of oxylijemoglobin, in acid solution two bands almost 

 exactly in the position of the bands of acid hsematoporphyiin, but 

 in alkaline solution showing only two bands, in the same position 

 as in the neutral solution, and not the four bands of alkaline 

 hfematopoi'jihy rin . 



The first of these was obtained from the cotyledons of the Cow 

 by crushing the tissues, after removal of (at any i-ate most of) the 

 haemoglobin by water, and from the virgin uterus of the Sheep by 

 drying the tissues, toith the contained hcemoglobin, ftnd powdering; 

 the second was obtained from the cotyledons of both Cow and Sheep 

 by the second method, involving the retention of haemoglobin with 

 the pigment. It seems probable that the first pigment is present 

 as well as the second, though masked by it, in the cotyledons of 

 the Sheep. 



That the second pigment is not produced from the included 

 haemoglobin by the treatment adopted is proved, first, by its 

 absence in the virgin uterus of the Sheep, and, second, by the 

 failure to get a solution showing the bands by boiling dried 

 haemoglobin in absolute alcohol. This second pigment then, if not 

 the first, would appear to be new to physiology, though related 

 to hsematoporphyiin. The name h?ematoph?ein may be provi- 

 sionally given to it. It is a haemoglobin derivative and from it 

 bile-pigments may be formed. This Avill be shown in the next 

 section. 



6. The ^'' Hippomanes" or Allantoic Bodies. 



Although the curious rounded or elongated, often flattened, 

 sometimes soft, sometimes hard and bi-ittle bodies found floating 

 in the allantoic fluid have been familiar objects for many centuries, 

 the exact mode of their formation has not, to the best of my 

 knowledge, been yet accui-ately described. 



They occur in both the Cow and the Sheep, being larger in the 

 latter. Their colour in the former case is whitish or pale yellow, 

 in the latter a dirty brown. 



Their origin will be considered first in the Sheep. Fi-om 



