66 



THE VENOMS OF CERTAIN IHASATOPHIDEA 



Experiment No. 26. 



Normal 



mm. sec. 



10 

 30 

 00 

 30 

 30 

 30 

 30 

 30 

 30 



Pulsations 

 per minute. 



320 



315 



330 



330 



330 



335 



340 



320 



330 



Normal 



Time: 

 min. sec. 





 10 

 20 



1 00 



2 00 



00 



Pneumogastric nerves cut. Injected intravenously 0.006 

 gram dried Cobra venom prepared as in the foregoing 

 experiment. 



Convulsions ; asphyxia ; death in 2-J minutes. 



Experiment No. 27. 



Pulsations REMARKS, 



per minute. 



390 Pneumogastric nerves cut. Injected intravenously 0.003 

 gram dried Cobra venom dissolved in 1 c. c. distilled water. 



396 

 390 

 360 

 354 



Clot in canula. 

 Dead of asphyxia. 



The Actions of Pure Venoms on Animals in which Sections of the Pneumogastric 

 Nerves and of the Upper Cervical Portion of the Spinal Cord had been made. — 

 After isolation of the heart from the nerve centres by making section of the 

 pneumogastric nerves and spinal cord in the middle or upper cervical region, and 

 maintaining the animal alive by means of artificial respiration, we find that the 

 pulsations of the heart are almost invariably slightly diminished in frequency 

 upon use of venom. Seven experiments were made : three with the venom of the 

 Crotalus adamanteus ; one with the Crotalus horridus ; one with the Ancistrodon 

 piscivorus ; one with the Ancistrodon contortrix, and one with Cobra. In one expe- 

 riment with the Crotalus adamanteus in which two doses were given, there occurred 

 a diminution after the first dose, while there was a marked increase after the second. 

 In the experiment with the Crotalus horridus there was but little alteration. 



Experiment No. 28. 





Time: 



Pulsations 



min. sec. 



per minute. 



Normal . . . 



240 



10 



235 



20 



230 



30 



225 



40 



215 



1 00 



210 



1 20 



210 



1 40 



210 



2 40 



REMARKS. 



Pneumogastric nerves and cord cut. Injected intravenously 

 0.003 gram dried venom of the Crotalus adamanteus dis- 

 solved in 1 c. c. distilled water. 



Dead. 



