108 



THE VENOMS OF CERTAIN THANATOPHIDEJE, 



normal animals ; the effects, however, appear to be less decided than in animals 

 with the pneumogastrics intact. , Here, as in the previous experiments, the copper- 

 venom-globulin exhibits comparatively little effect on the pressure. 



Of the four experiments which were made with globulins from the Crotalus 

 adamanteus, one was made with the water-venom-globulin; two with the copper- 

 venom-globulin, and one with the clialy sis-venom-globulin. It will be noticed that in 

 several instances considerable rises of pressure occurred accompanied by struggles ; 

 the former effect being, no doubt, due to the latter, and not to a peculiar action 

 of the globulin. 



Experiment No. 55. 



Normal 



Time : 

 min. sec. 



10 

 20 

 30 

 1 00 

 1 40 

 3 40 

 5 40 



Pressure 

 m. m. 

 116 

 100 

 100 

 110 

 106 

 110 

 110 

 108 



Injected intravenously 0.0011 gram ivater-venom-globulin from 

 the dried venom of the Crotalus adamanteus. 



Clot in canula. Animal killed by pithing. 



Experiment No. 56. 



Time : 



Normal 



min. sec. 



10 

 20 

 30 

 40 

 10 

 10 

 10 

 10 

 10 



1 

 3 



5 



T 



9 



23 10 

 23 20 

 23 40 



23 55 



24 00 

 24 15 



Pressure 

 m. m. 

 130 

 132 

 132 

 132 

 132 

 132 

 132 

 128 

 128 

 128 

 136 

 130 

 132 

 132 

 116 

 116 



Injected intravenously 0.0024 gram copper-venom-globulin 

 from the dried venom of the Crotalus adamanteus. 



Injected a similar dose. 



Respiration greatly slowed. 



Animal broke loose. Killed by pithing 



Experiment No. 57. 



Time: 



Normal 



20 

 40 

 50 

 50 

 50 

 50 

 50 



Pressure 

 m. m. 

 116 

 116 

 116 

 116 

 116 

 116 

 116 

 112 



Injected intravenously 0.0012 gram copper-venom-globulin 

 from the dried venom of the Crotalus adamanteus. 



