KARYOLYSUS. 



155 



epithelium of the Vertebrate host, a lizard, through the 

 ingestion of the faeces of the nymph or of the nymph itself. 

 The sporozoites pass to the blood-vessels and penetrate the 

 endotheUal cells, where schizogony takes place. Certain 

 merozoites enter the red blood- corpuscles as gametocytes 

 and appear as Hsemogregariaes. The gametocytes are taken 

 up by the mite, in the gut of which gametogony takes place 

 and the oocyst is formed. 



Bemarks. — The genus owes its names to the fact that the 

 nucleus of the host-cell is often karyolysed and fragmented, 

 but this character cannot be regarded as of generic value. 



92. Karyolysus jorgei de Mello & de Meyrelles. (Fig. 71.) 



■\Karyolysus jorgei, de Mello & de MeyreUes, 1937, pp. 119-41, pi. vi, 



4 text-figs. 



Gametocytes, occurring in the red blood- corpuscles in the 

 peripheral circulation of the lizard, are elongate oval, marked 



Fig. 71. — ^Life-cycle of Karyolysus jorgei de Mello & de Meyrelles. 



A, male and female gametocytes in peripheral blood ; 



B, endoglobular cycle in capillaries producing macro- 

 cysts with four merozoites ; G, endothelial cycle in liver 

 and lungs producing microcysts with eight leishmaniform 

 merozoites ; D, free merozoites which may invade either . 

 the red cells or endothelial cells. (After de Mello and de 

 Meyrelles.) 



by a strong limititig membrane, and contain a large central 

 nucleus, a smaller roundish paranuclear body, and near the 

 opposite pole a more or less irregular zone named as a polar 

 capsule. The gametocytes are sexually differentiated. In 



