TOXOPLASMA. 



205 



Stained by Giemsa the nucleus is coloured a brilliant red ; 

 the cytoplasm clear and faintly blue. Small or large forms, 

 3-7 fi in size. Schizogony in the hepatic cells, more rarely 

 in the peripheral blood and bone-marrow. Sometimes 

 binary division takes place, when rudimentary karyokinetic 

 figures can be demonstrated. Sporogony not known. 



Habitat. — Mononuclear leucocytes of the pigeon : Portu- 

 guese India, Mapu9a (Bardez). 



142. Toxoplasma cuniculi Splendore. (Fig. 101.) 



Toxoplasma cuniculi, Splendore, 1909 a, p. 109 ; 1909 b, 

 pp. 462-5: Carini, 1909, pp. 465-9, figs. 1-14; 1910, p. 167; 

 1911a, pp. 518-19; Bourret, 1911, p. 373; Castellani & 

 Chalmers, 1919, pp. 489, 490; Brug, den Heyer, & Haga, 1925, 

 pp. 232-8, pis. i-vi ; Wenyon, 1926, p. 1047 ; Reichenow, 1929 

 p. 965 ; ISToller, 1931, p. 805. 

 '^Toxoplasma ctXniculi, Krishnan & Lai, 1933, pp. 1049-50, pi. xlv. 



Intracellular in the endothelial cells, or leucocytes, or in the 

 body fluids. Crescentic in shape, pointed at both ends ; 

 but one end is frequently more pointed than the other. Nucleus 

 central and has a definite karyosome. Occurs singly or in 

 groups. Reproduction by schizogony has also been described. 



Remarks. — Krishnan and Chiranji Lai (1933) found this 

 infection in two out of twelve rabbits that had received a course 



Fig. 101. — Toxoplastna cuniculi Splendore. A, a large cluster of parasites. 

 B, a large mononuclear cell from spleen showing a dividing 

 form and a group of parasites. (After Krishnan and Lai.) 



of fifteen injections of Indian ink and colloidal iron, followed 

 by three intravenous injections of a culture of Leishmania 

 donovani. Eight weeks after the last injection the two rabbits 

 began to look sickly and lose weight. They suffered from 

 diarrhoea and died. Smears from spleen, Hver, bone-marrow, 

 and heart-blood showed large numbers of intracellular and 



