H^MOPROTETJS. 



215 



■enter other endothelial cells and again become schizonts. 

 Others enter the red blood- corpuscles and are seen as minute 

 cytoplasmic bodies with a single nucleus and often a vacuole 

 (fig. 104, A-j^, A^). Sometimes as many as a dozen young forms 

 may be present in a single corpuscle, and thus in dry films, 

 by an approximation and overlapping of the parasites, falsely 

 suggest a schizogony. The corpuscles with such multiple 

 infections generally die, so that it is rare to find even two 

 fully developed gametocytes in a single corpuscle. The young 



I'ig. 105. — Development of Heemoproteus columbse Celli & San Felice on 

 stomach- wall of Lynchia maura. A, flattened stomach 

 showing numerous oocysts of various sizes ( X c. 72) ; 

 B, edge of stomach more highly magnified, showing 

 mature and immature oocysts with pigment granules 

 ( X c. 450) ; G, intact oocyst and ruptured oocyst, with 

 discharged sporozoites and residual cytoplasm { X c. 600) ; 

 D, free sporozoites. (From Wenyon, after Adie.) 



gametocyte becomes elongate, and granules of brown or black 

 pigment appear in the cytoplasm (fig. 104, B, C) : it grows 

 roimd one side of the nucleus, pushing it to one side of the 

 oell, but the latter retains its original shape and size. The 



