LAVERANIA. 261 



Laverania malarise, Thomson & Woodcock, 1922, pp. 1530-6, 



pis. Ixv, Ixvi ; text-figs. 545, 546. 

 Plasinodium falciparum, Hegner & Taliaferro, 1924, pp. 327—9, 



pi. ii, figs. 9-16. 

 Laverania falciparum. Stiles & Hassall, 1925, p. 42. 

 Plasmodium falciparum, Craig, 1926, pp. 433-52, figs. 74-8 ; Wen- 

 yon, 1926, pp. 934-41, pis. vii-ix, pi. xiii, figs. 16-40 ; figs. 391, 

 401-3; Hehir, 1927, pp. 166-73, pi. xii, figs. 76-117; pi. xiii, 

 figs. 118-29 ; pi. xiv, figs. 1-8 ; figs. 59-60. 

 '^Plasmodium falciparum, Knowles, 1927, pp. 14-20, pi. iii, figs. 1-24 ; 

 1928, pp. 392-400. pi. xiii. 

 Laverania malarix, Reichenow, 1929, pp. 987-97, figs. 958-73, 

 975 a-e. 

 '^Plasmodium falciparum. Row, 1929, pp. 1120-5, pis. Ixxxviii, 

 Ixxxix ; 1930, pp. 221-6, pis. xxiii, xxiv. 

 Plasmodium' falciparum, Aragao, 1930, pp. 41-56, 1 pl. ; Kudo, 

 1931, p. 286, fig. 121, h-n ; Calkins, 1933, p. 407, pl. i, figs. 13-17 ; 

 pl. ii, figs. A-L ; Chaoulitch, 1936, pp. 716-22 ; Brumpt, 1936, 

 pp. 418-24, figs. 185-7 ; Coatney & Roudabush, 1936, p. 339. 

 Plasmodium immaculatum, Giovannola, 1935, pp. 90-1. 

 ^Plastnodium tenue, Stephens, 1914, pp. 169—72. 



The so-called Plasmodium tenue, Balfour & Wenyon, 1914, p. 353. 

 ■fPlasmodium tenue, Sinton, 1922, pp. 215-35, pis. ii & iii ; Knowles, 

 1923 a, p. 276 

 Plasmodium tenue, Wenyon, 1926, pp. 951-2, fig. 405 ; Craig, 1926, 



pp. 464-70. fig. 81. 

 '\Plasmodium tenue, Kjiowles, 1928, p. 404, fig. 93. 

 Plasmodium tenue, Reichenow, 1929, p. 988, fig. 961. 



The Cycle in Man. — Young trophozoites are very small, 

 often seen as a tiny bead of chromatin, "with a wisp of blue- 

 staining cytoplasm adhering to the margin of the red corpuscle 

 (the marginal or accole form). Multiple infection of red 

 blood- corpuscles is very common, many of them containing 

 two, three, or sometimes a larger number. The smallest 

 " rings " are very narrow, appearing as a thin blue hne 

 surrounding a vacuole, with a red-staining granule of chromatin 

 or nucleus protruding at one side, occupying no more than 

 one-sixth of the diameter of the red blood- corpuscle. Chroma- 

 tin often rod-like, and divides very early into two granules 

 (nuclei). Fully grown trophozoites may be as large as half 

 the size of the red blood-corpuscle, and the cells containing 

 these big rings show Maurer's dots. Occasionally more 

 irregular or amoeboid forms occur. Infection is usually 

 heavy, as many as 25 per cent, of the corpuscles being found 

 infected. Infected red corpuscles do not become enlarged 

 (as they do in infections with Plasmodium vivax), but on their 

 surface appear red- staining markings usually known as 

 Maurer's dots (the markings were actually first described 

 by Stephens and Christophers, who regarded them as clefts 

 in the red corpuscle in which the red of the stain is deposited) . 

 Maurer's dots are larger and fewer in number than Schiijffner's 

 dots (which are found in P. vivax), and are best seen in deeply 

 stained films : they are stellate or crack-hke rather than dot- 

 like, and stain brick-red rather than the bright pink of 



