ACKNOWLEDGEMENTS 



The author sincerely wishes to acknowledge the support 

 of the numerous individuals who contributed to this under- 

 taking. Without their individual efforts on my behalf, a 

 difficult task would have been arduous at best. 



The faculty of the Department of Microbiology and 

 Cell Science have been without exception generous of their 

 time, facilities and expertise, all of which were frequently 

 sought and received. I am truly grateful for having had 

 their help and teachings, in particular the members of my 

 graduate committee: Drs. Ed Hoffmann, Bill Clem, Ken 

 Noonan and Jim Preston. 



Dr. Preston, as my major professor who unsuspectingly 

 opened his lab to me, contributed beyond the limits defin- 

 able in this simple statement. In the final analysis, it 

 is his patience that sustained these efforts through com- 

 pletion. 



The understanding of my personal friends and family 

 has been essential to my well being. Their confidence in 

 mc throughout reassured and stabilized my goals. 



Thank all of you. 



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