150 



of toxin density to cell specific cytotoxicity will be of 

 great significance to future studies of drug targeting. 

 The nature of the interaction between ADGG-Con A conju- 

 gates and their cell receptor can be more throughly in- 

 vestigated by comparing the results of this study to those 

 obtained with conjugates of ADGG and anti-Con A receptor 

 antibodies. These will allow a more thorough definition 

 of the mechanisms of binding and endocytosis of lectin on 

 the cell surface. 



Alpha-amanitin would thus appear to be a logical 

 choice for continued investigations of protein-inhibitor 

 conjugate development and targeting of cytotoxic drugs. 



