510 
were separated by means of hydrochloric acid and ether and then 
weighed. 
They were once more dissolved in the calculated quantity of 
N/,, potassium hydroxide, and calcium chloride (1.5 grm. for each 
10 e.e.) again added. After twenty-four hours the precipitate was 
filtered and washed with a little calcium chloride solution (1.5 grm. 
in 10 ¢.c.). The precipitate is added to that first obtained. 
Separation of B-, d-, and e-truxillic acids. The calcium salts are 
treated with hydrochloric acid and ether, and the acids dissolved in 
the calculated quantity of N/10 potassium hydroxide. Twice the 
volume of water is then added, and as much N/10 barium chloride 
solution as was used of N/10 potassium hydroxide. After twenty- 
four hours the precipitate is filtered and washed with water. It 
consists of the barium salts of 8- and e-truxillie acid. The acids are 
extracted from the filtrate by means of hydrochloric acid and ether. 
They are redissolved in N/10 potassium hydroxide. Twice the volume 
of water is added, and as much N/10 barium chloride as was used 
of N/10 potassium hydroxide. In this way a little more 8- and «- 
truxillie acids are obtained as barium salts. The filtrate now obtained 
yields d-truxillie acid with hydrochleric acid and ether, which, if 
necessary, can be purified by recrystallisation from boiling water. 
The precipitated barium salts are boiled with water, cooled, and 
filtered. Hydrochloric acid is added to the filtrate. If a precipitate 
is formed, the above treatment is repeated until no precipitate is 
obtained. The filtrates yield e-truxillie acid on treatment with hydro- 
chlorid acid and ether. This may be purified, if necessary, by 
recrystallisation from boiling water. The undissolved barium salt 
gives B-truxillie acid with hydrochloric acid and ether. 
Separation of a-, y-trurillic acids and p-cocaic acid. To the filtrate 
from the precipitated calcium salts 8.5 grms of anhydrous calcium 
chloride per 10 c.c. is added. The precipitate is filtered after twenty- 
four hours and washed with a solution of calcium chloride prepared 
by dissolving in water as much calcium chloride in grams as there 
are c.c.’s of water. The acids are extracted from the filtrate, and 
these are subjected to a similar procedure in order to separate a 
small quantity of p-cocaic acid as calcium salt. The precipitated 
calcium salt gives g-cocaic acid, when treated with hydrochloric acid 
and ether. This may be recrystallised from boiling water if necessary. 
The filtrate from the precipitated calcium salt gives a- and y- 
truxillie acid with hydrochloric acid and ether. In order to separate 
these the acid mixture is boiled with water (25 c.e. per 0.1 grm.) 
with a reflux condenser for half an hour and is then filtered hot. 
