836 
Erp. 2. */,°/, cocain solution nerve irresponsive after 43 min. 
pe ake oh On ER 55 5 sb EN NE 
DCE hl 5 5 5 yt AAN es 
” 5. “fe */, Ld Te) LE > 2 43 LE) 
” 6 whe ae LE) ” EE) ” ” 42 ” 
99 le “fos Wp ” ” LE 2 ” 45 ” 
2, 8. We he ” ” ” ” EE) 41 ” 
»? 9. “Ya de ” ” LE) ” ” 42 ” 
dd 10. “eo Wb ” id ” ”? ” 43 EE) 
It follows, then, that on an average the nerve is irresponsive in 
*/,°/, cocain solution in 48 minutes. 
We now proceeded to ascertain the adsorbent power of human 
bloodserum. 
Exp. 11. The liquid consisted of: 0,1 ec. 5°/, cocain solution 
+ 1,9 ce. of serum, i.e. a concentration of */,°/, cocain in serum. 
In this case the muscle remained normally responsive for a whole 
hour, so that the effect of 5 mgr. cocain is eliminated by 2 ce. 
of human serum. The process of this experiment will be seen from 
the curve in Fig. 3. 
Reading taken of the inductorium 
60 
minutes 
Fig. 3. Effect of 1/,0/, cocain in human serum on the nervus ischiadicus 
of a muscle nerve preparation of Rana esculenta. 
After this Exp. 11 was repeated with dog’s serum. 
Exp. 12. The liquid used was 0.1 ec. 5°/, cocain + 2 ce. of 
dog’s serum, that is about */, °/, cocain in serum: (see table p. 837. 
Here also the inhibiting influence of the serum can be seen distinctly. 
A similar result was obtained in exp. 13 with cat’s serum and in 
