847 
Stimulation after: | Reading laken of Control 
2 min. | 1.9 1.9 
4 | 1.8 1.9 
6 1.7 1.9 
8 1.68 1.9 
10 1.66 1.9 
12 1.64 1.9 
14 1.64 1.9 
16 1.62 1.9 
18 1.6 1.9 
20 1.56 1.9 
22 | 1.4 1.9 
24 1.2 1.9 
26 1.1 1.9 
28 — 1.9 
We see from this that the cocain has again been detached. Of 
the ecocain thus obtained. Dr. Le Heux determined the melting 
point, which was 96,6° (uncorrected), which again proves that the 
cocain has not been decomposed (not even partially), but that only 
a physical adsorption has taken place. (Normal melting point of 
cocain hydrochl. 98°). 
Since it had now become evident that brain-substance is capable 
of adsorbing cocain, we ascertained whether one of the familiar 
brain lipoids viz. lecithin’), could also exert this action. 
Erp. 35. Liquid: 1 ee. 5°, lecithin solution +1} c.c. aqua 
distillata + 24 ee. Rincer (1.2 °/,) without cocain. In this experi- 
ment the responsiveness of the nerve had hardly changed, from 
which we see that lecithin of itself does not injure the nerve. 
Erp. 36. 1 ec. 5°/, lecithin solution + '/, ec. aq. dest. + 1 ce. 
5°/, cocain + 2'/, ce. Ringer (1.2°/,), that is 1°/, cocain hydro- 
chlorieum in 1°/, lecithin. 
') The lecithin was supplied by Menck. 
Proceedings Royal Acad. Amsterdam, Vol. XXII. 
