936 
as indeed the heart of this animal is not injured by hypophysin. 
It is unlikely that Bornur’s interpretation applies to our case, 
1. because peptone intensifies the adrenalin action in doses many 
times smaller than those which affect the circulation in the cat, and 
even a gradual rise of the blood-pressure occurs after the peptone- 
injection, (see also Fig. 1) and 
2. because peptone, as recorded in our first communication, has 
also an intensifying influence upon the pilocarpin-action on surviving 
organs. 
Another observation of ours may serve to explain why the dialy- 
sate influences the adrenalin-action on the rise of the bloodpressure 
in the decapitated cat and not in the rabbit. As stated before, in our 
investigations we hardly ever found in decerebrated rabbits an 
increase of the adrenalin-action through peptone or its dialysate. In 
One case however we detected a very marked action of the dialy- 
sate; this case has been illustrated in fig. 4. 
Fig. 4. Decerebrated rabbit. Bloodpressure Abnormal reaction to adrenalin and 
to adrenalin + dialysate of Witte’s peptone. 
Here the minimum quantity of adrenalin that produced a distinct 
rise of the bloodpressure, was rather large viz. 0.01 mgr. In two 
successive cases this quantity gave a rise of 16, respectively of 
22 mm. Hg. (a). After injection of a small quantum of peptone- 
dialysate the action of the same amount of adrenalin on the rise of 
the bloodpressure increases largely, viz. 40 and 36 mm. mercury (6, c). 
After two more dialysate injections the rise of bloodpressure, brought 
about by 0.01 mgr. of adrenalin amounts to 60 mm. mercury, ie. 
considerably higher than before (d). 
In 11 experiments with the decerebrated rabbit this was the only 
ease, in which the peptone-dialysate had an intensifying influence 
on the adrenalin, and it is rather remarkable — especially in con- 
nection with the experiment with a decapitated cat (fig. 1) described 
in the beginning of this communication, — that this particular rabbit, 
