966 
nature that there seemed to exist a flagrant contradiction between 
the course of the blood formula of the different types of white blood- 
corpuscles and the cells found in the exudation. 
The numbers given by the different researchers as regards the 
percentage of the different kinds of white blood corpuscles in the 
blood of rabbit greatly diverge. Through the examination of a 
large number of rabbits we found the total number in 1 c.mm 
of a drop of the circulating blood as follows: total amount 
7.500 — + 12.000 of which, on an average 25—30°/, were 
polynuclear cells and 70—75 °/, mononuclear cells, mostly 
smaller and larger lymphocytes. Only very exceptionally as much 
as 50°/, polynuclear cells were found. This blood-formula in the 
rabbit is also, with respect to the proportion between the polynuclear 
and mononuclear cells, near enough just the reverse of what we 
find in man. More or less the same numbers are given by JORGENSEN *). 
One and the same rabbit exhibits on the whole oscillations of only 
minor importance. 
After the injection of NaCl. 0.9°/, however, the change is very 
marked. After the lapse of a few hours the blood corpuscles decreased 
in number to but 1,500—2,500 i.e. to about '/, the original number; 
during a short period the polynuclear cells had more or less disap- 
peared from the blood, but also the lymphocytes decreased greatly 
in number. As an example I quote the following tabula: 
Rabbit I. | Rabbit II. 
Date. | Time. | Lympho- | Polynucl. | Lympho- | Polynucl. | REMARKS. 
cytes. jleucocytes.| cytes. leucocytes.) 
Jan. 12 /10.30a.m.| 10.175 2.500 7.650 2.075 
12.30p.m. — | — — — Intraperitoneal injection 
of 200 cc. NaCl 0.9%. 
2 5 2.950 275 2.200 1b 
3 Fr 2.315 15 1.000 112 
4 B 1.700 800 1.300 500 
Jan. 13 | 9.30a.m.| 13.300 5.500 5.725 6.525 
10.30 , — — — == Intraperitoneal injection 
of 200 cc. NaCl 0.9%. 
11.30 „ 7.950 5.800 4.050 1.850 
2 p.m} 3.100 1.075 2.000 525 
We therefore see that the polynuclear cells rapidly diminish. The 
lymphocytes diminish more gradually. After 3 to 5 hours this decrease 
1) Skand. Arch. f. Physiol., XXXII, 4/6, p. 253. 
