86 Further Observations on Snake-Poisoning. 



place. The whole subject, therefore, requires reconsidera- 

 tion. The facts are as I stated, but possibly have relations 

 hitherto unknown to me. 



From the first I stated these white cells arise in a structure- 

 less molecular matter, nucleus first, cell- wall after ; and that 

 in some manner they took the place of what is called fibrine, 

 and, further, that the higher the thermometer for the time 

 being the more numerous and larger were these bodies. 



The changes, therefore, take place when the blood is 

 stagnant, but still retained within the veins. 



Now it is fortunate that I can direct the attention of this 

 Society to some other phenomena in the growth of cells as 

 observed by Dr. Onimus and recorded in the " Journal de 

 l'Anatomie et de la Physiologie," 1867, and just received in 

 Melbourne. He disbelieves in the doctrine of Virchow that 

 omnis cellula e celluld, and holds that cells arise in an 

 amorphous blastema. 



This agreeing with the origin of the white cells I have 

 described, let us follow Dr. Onimus in his experiments and 

 conclusions. 



The fluid from a recent blister was filtered so as to obtain 

 a fluid containing no kind of form, neither white corpuscles 

 nor epithelial scales. This fluid was enclosed in small tubes 

 of gold-beaters' skin, and placed beneath the skin of a live 

 rabbit. 



After two hours — the serum was still transparent, although 

 it had lost its primitive citrine colour. In 

 it were seen a few white cells and granules. 



After 24 hours — the serum was turbid, and contained a 

 great quantity of white cells and granules. 



After 36 hours — the serum was quite white, milky, and 

 composed entirely of white cells and 

 granules. The white cells having all the 

 characteristics of white corpuscles of the 

 blood. 



Increase of animal temperature aided the production of 

 the white cells. 



iVb white cells, nor any sort of anatomical element ivas 

 formed in the serum of blisters, from which the fibrine had 

 coagulated. 



The presence of white cells artificially added to serum 

 from which the fibrine had separated, had no effect in 

 causing further development of white cells. 



