4 BULLETIN" 942, U. S. DEPARTMENT OF AGRICULTURE. 



she staggered when walking, appearing " stiff behind." During this 

 day and August 31 her condition remained much the same. She was 

 depressed, held the head high much of the time, and staggered or 

 wabbled when walking. On September 1 the uncertain movement 

 in walking had largely disappeared, but she was rather inactive. On 

 September 2 she had apparently entirely recovered. There was no 

 elevation of temperature during this sickness. 



This animal received several doses of eserin and pilocarpin, but 

 apparently the remedy had no beneficial effect. 



On September 27 another experimental feeding was made, the 

 sheep at this time weighing 99 pounds. She received 2.559 pounds, 

 green weight, per 100 pounds of animal, between 3.20 and 3.50 p. m. 

 On September 28, at 7.40 a. m., she stood with head held high and 

 nose extended, was somewhat bloated, and unsteady on her feet, this 

 latter characteristic being most marked in the hind legs. 



At 9.09 a. m. the pulse was weak, respiration irregular, and the 

 animal staggered badly. This condition continued, the weakness and 

 discomfort increasing. Plate II, figure 1, taken at 10.46 a. m\, when 

 she was somewhat salivated, illustrates the general condition. At 

 11.15 a. m. she was found down and unable to rise. She went into a 

 spasm at 11.21, with the head drawn toward the breast. Another 

 spasm followed at 11.35, the head being first drawn down and then 

 thrown back in the position of opisthotonos. 



The pulse at this time was rapid and weak and the respiration 

 labored. Until about 6 p. m. there was an almost continuous series 

 of spasms, the time between successive ones rarely being as much as 



5 minutes. At noon running movements appeared in connection 

 with the spasms. The spasms were very violent for the most part, 

 opisthotonos being very marked and sometimes the head was struck 

 upon the ground with great violence. Plates II and III show some 

 of the attitudes assumed between 11.36 a. m. and 1.45 p. m. 



About 6 p. m. the animal became comparatively quiet, and re- 

 mained so until 8.50 p. m., when a series of continuous spasms com- 

 menced, which were terminated by death at 9.23 p. m. 



Most of the time the pulse was rapid and weak. The respiration 

 varied, sometimes being very rapid, and at others slower and labored. 

 Text figure 2 shows the curve of temperature. It will be noted that 

 there were three high periods, the maximum, 109.6 F., being at the 

 time of death. The low period between 6 and 8 p. m. is correlated 

 with a time of comparative quiet, but this is not true of the 3 o'clock 

 low, for the spasms were practically continuous during the after- 

 noon. The immediate cause of death was respiratory paralysis. 



The autopsy was made immediately. There was clotted blood in 

 the trachea and bronchi, and the lungs were congested. The stom- 



