BULLETIN 166, U. S. DEPARTMENT OF AGRICULTURE. 



[Reverse.] 

 RECORD OF REACTORS. 





Disposition of reac- 

 tors (slaughtered 

 or quarantined). 



Date: 





No. of 







animal. 









(Q. D. Form 69.) 

 U. S. Department of Agriculture, 



BUREAU OF AXTMAL INDUSTRY. 



























Record of ophthalmic mallein test. 

















Name of person making test: 























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EFFECT OF THE TEST ON GLANDERED AND HEALTHY ANIMALS. 



As soon as the mallein is introduced into the eye practically all 

 animals show a lacrimation, increased reddening of the conjunctiva, 

 and slight photophobia. Xo significance should be given to these 

 symptoms. The}" disappear in one to two hours. 



Glandered animals are hypersensitive to mallein in a way that the 

 administration of small quantities of mallein produces local inflam- 

 matory processes. In larger quantities it produces a febrile general 

 reaction. The hypers ensitiveness appears as a rule during the third 

 week after the infection, and reaches its height in the first few months 

 after the infection. In the subsequent course it may subside in 

 retrogressive cases even to the degree observed in healthy animals, 

 but even in these cases various conditions may bring on an increased 

 sensibility. 



The characteristic manifestations of the reaction for glanders 

 commence as a rule in from 5 to 6 hours and last 24 to 36 hours, some- 



