GRANULAR VENEREAL DISEASE AND ABORTION IN CATTLE. 43 



horn the chorion was firmly adherent to the cotyledons and attempts to detach it 

 resulted in its giving way and the chorionic tufts being more or less completely re- 

 tained in the cotyledonal crypts. 



The cotyledons were 2 to 3 inches in their greatest diameter and deeply injected, 

 brownish-red in color. The intense injection extended one-half inch or more into 

 the cortical substance of the cotyledons, after which they appeared a dirty, necrotic- 

 like, yellowish-gray color. The cotyledons were hard, swollen, and infiltrated. 



The afterbirth was retained due to cotyledonitis, which had evidently antedated 

 the expulsion of the fetus and would probably have resulted eventually, had the heifer 

 lived, in total necrosis and sloughing of the cotyledons. The placenta was not 

 markedly putrid. There was but little if any fetor present. The odor was rather 

 of an unpleasant sweetish character. 



The chorionic tufts were soft, adhesive, and necrotic-looking. The tufts, where 

 detached from the cotyledons, would stick to the fingers. The amniotic and allantoic 

 cavities were empty except for scattering fragments of tissue d6bris or coagula. 



The utero-chorionic ca\ity was filled with a puslike substance throughout its 

 entire area. The exudate was dirty gray, flocculent, floating in thinner liquid. It 

 wanted that adhesiveness usually observed in the abortion exudate in closed uteri. 

 The admixture of fetal fluids had served to change the physical character of the 

 exudate. 



The uterine mucosa was inflamed, thickened, uneven, and granular in appearance. 

 In some areas there was a dirty-gray firmly adherent exudate; in other areas the mucosa 

 was naked, injected, inflamed, and showed petechial hemorrhages. The fetus was 

 28 inches from occiput to sacrum. 



Case 3.— A 2-year-old heifer which had been driven a distance of 25 miles and yarded 

 overnight in the Denver stockyards on June 2. At 7.45 a. m. June 3 she expelled 

 an 11-inch fetus with the fetal sac complete. The heifer was slaughtered 4 hours 

 after she aborted. 



The carcass was thin and emaciated. The mammary gland was enlarged as though 

 parturition were impending. After slaughter there escaped from the vulva one-half 

 ounce or more of a dirty-grayish, flocculent exudate, faintly tinged with red. After 

 the removal of the skin no traumatism of the body walls could be detected. Granular 

 vaginitis was well marked, but not intense. The uterine walls were one-fourth of an 

 inch thick, vascular, and petechial. 



The uterine cavity, including both horns, contained 3 or 4 ounces of a dirty-looking, 

 flocculent exudate, floating in a thin watery liquid. The clumps of exudate were 

 somewhat viscid, and the masses were largely adherent about the pedicels of the 

 cotyledons. 



The exudate had the general appearance of that described as the typical exudate of 

 contagious abortion, but its glutinous character had been modified by the presence in 

 the cavity of portions of the amniotic and allantoic fluids. 



The cotyledons were 1£ inches in diameter, hemorrhagic in the cortical area, and 

 the surface was scarlet in color, like oxygenated blood. The cotyledonal crypts con- 

 tained some chorionic tufts. 



The chorion was edematous, one-half inch thick, and comparatively free from odor. 

 The chorionic placental areas were pale, soft, and sticky. 



Case 4-— Inoculated May 2, 1911 (10 c. c. of abortion-bacillus culture in the jugular 

 vein), aborted May 9 and killed May 10, 1911. A few cotyledons near the internal os 

 were scarlet. The cotyledons were covered more or less irregularly with a yellowish- 

 gray substance resembling pus in consistency, but more yellow. This was found 

 over the majority of the cotyledons. There was very marked edema beneath the mu- 

 cosa near the internal os, and in this region were also several areas of redness. 



Case 5. — Inoculated May 2, 1911 (15 c. c. of abortion-bacillus culture in the jugular 

 vein), aborted May 28 and killed May 29, 1911. The placenta showed considerable 



