18 BULLETIN 800, U. S. DEPARTMENT OF AGEICULTURR. 



of these cases is given in Table 1. In three of the experiments the 

 plant, mixed with hay, was fed to the animals. In all other cases 

 the feeding was by the balling gun, so that the animals received the 

 material in a very short time. It does not seem necessary to give the 

 details of all these cases, as they were very simple. Two cases that 

 were fairly typical have been selected for an extended account. 



Sheep 478. 



This animal was an old ewe, in fair condition, weighing 100.5 

 pounds. On June 19 at 10.30 a. m. its temperature was 102.8° F., 

 pulse 108, and respiration 39. Between 10.38 and 10.40 a. m. it was 

 given, with the balling gun, for each hundredweight of animal, 0.165 

 pound of Asclepias gaZioides from Hotchkiss, Colo. The animal was 

 kept under observation during that and succeeding days and showed no 

 symptoms of poisoning. The highest temperature reached was 103.4° 

 F., at 11 a. m. June 19. The animal, then weighing 114 pounds, was 

 brought in August 19, 1918, for another experiment with the plant. 

 At 10.03 a. m. its temperature was 102.1° F., its pulse 90, and respira- 

 tion 48. At 11.09 it was given, for each hundredweight of animal, 

 0.11 pound of green Asclepias galioides which had been collected near 

 High EoUs, N. Mex. There Avas no result from this feeding. 



On August 28, when the animal weighed 111 pounds, another ex- 

 periment was made. At 9.50 a. m. its temperature was 100.9° F., 

 pulse 60, and respiration 36. At 11.35 a. m., for each hundredweight 

 of animal it was given 0.138 pound of green plant of Asclepias 

 galioides which had been collected near Paonia, Colo. From this 

 feeding there was no result. On the next day, August 29, at 10.23 

 a. m., for each hundredweight of animal 0.138 pound of green plant 

 of Asclepias galioides was given. This experiment, too, was without 

 effect. On September 2 it was given 0.147 pound of green plant 

 per hundredweight of animal, again without effect. On September 

 5 at 2.30 p. m. it received 0.167 pound of green plant per hundred- 

 weight of animal, the material having been collected near Paonia, 

 Colo. The animal was kept under observation and no symptoms 

 were noticed until 11.35 a. m. September 6. At that time it went 

 down on its knees and lay stretched out npon the stomach. A sub- 

 cutaneous injection of one-fourth grain of arecolin was given at 

 11.57. At 11.59 it was attempting to get up, but was vmable to do so. 

 The head was thrown back in the position of opisthotonos and then 

 at times drawn to the breast. The respiration was labored. 



Plate VII, figure 1, shows the attitude assumed by the animal at 

 11.57 and figure 2 at 11.58. Figure 2 is a characteristic attitude 

 when the animal was kicking about, with its head thrown far back. 

 At 12.02 p. m. the sheep was placed upon its feet but was unable to 



