THE WHOEKED MILKWEED AS A POISOlSrOUS PLAINT. 19 



stand. The respiration continued deep and labored. At 12.14: it 

 got upon its feet, ran across the pen and fell down. This was re- 

 peated two or three times. At 12.25 it was able to stand for a few 

 seconds, but fell forward again. At 12.31 it got up, fell twice, then 

 got upon its feet and fell forward across the pen. Figure 3, taken 

 at 12.21 p. m., shows its attitude when attempting to rise. Figure 4, 

 taken at 12.41 p. m., shows the attitude as it fell forward in crossing 

 the pen. Figure 5, taken at 12.45 p. m., shows the attitude when 

 lying more quietly. At 12.45 p. m., it was given another dose of 

 one-fourth grain of arecolin. In the spasms the eyes were dilated, 

 and the head was either drawn to the breast or thrown far back. 

 At 1 p. m. the animal seemed somewhat stronger, and it was taken out 

 of the pen. It was then able to hold its head erect. Figure 6 shows 

 the attitude assumed by the animal. After this the spasms were less 

 frequent and it seemed to be gaining in strength. At 2.14 p. m. it 

 was able to walk about 25 feet and a little later seemed to walk quite 

 normally. It continued to gain in strength until about 4.40 p. m., 

 when the condition seemed fairly normal. From that time it gained 

 steadily. 



The temperature was taken at intervals during this illness. At 

 6.35 p. m., September 5, it was 102.2° F., at 10.08 a. m., September 6, 

 100.2°, at 12.06 p. m., 103.7°, at 12.25, 104.4°, at 6.19 p. m., 103.3°, 

 and the next morning, September 7, at 8.13 a. m., 100.9° F. 



Sheep 476. 



Sheep 476 was an old ewe, weighing 81.5 pounds at the time of 

 experiment. On June 20 at 12.22 p. m. it was given 0.27 pound 

 of Asclejnas galioides per hundred pounds of animal. This was 

 given by the balling gun, and the feeding was finished in about three 

 minutes. The temperature at 2.20 p. m. was 101.9° F., pulse 102, 

 and respiration 30. At 3.45 the temperature was 102.6°, pulse 150, 

 and respiration 24. The respirations were deep and labored but 

 regular. The sheep was down on its side with the head thrown 

 back, and immediately went into a series of spasms. The legs were 

 extended and stiff. At 3.55 p. m., while lying up its side, it was 

 moving the legs as if running. The respiration was labored and 

 the expiration forced. The heart was beating nearly 200 times 

 a minute. The movements of the legs at times were slow and at 

 other times very rapid. At 4.07 p. m. there was frothing at the 

 mouth, bloating, and some gas was belched. These actions were 

 repeated every 2 to 5 minutes during the afternoon. The bloating 

 was very marked. At times the animal was trembling. In the 

 spasms the head was drawn back and brought to the breast, and 

 during that time the temperature went up to 105° F. The respira- 



