34 



BULLETIN 800, U. S. DEPARTMENT OF AGRICULTURE. 



Table 3. — Time elapsed beticeen feeding of plant and development of sijmp- 



fonis — Continued. 



Animal. 



Date and hour of feeding. 



Date and hour of symptoms. 



Time 

 elapsed 

 before 

 symp- 

 toms. 



1918.' 



Sheep 478 



Sheet) 480 . - 



September 5, 2.30 p. m 



September 6, 11.35 a. m 



Hours. 

 21 



June 18, 2.58 p. m 



.Tnne IS, FiJFi p. m 



2J 



Sheep 483 



Shpeo 492 



August 22, 11.10 a. m 



August 23, 7.15 a. m 



20 



Septemlier 11, 4.10p. m 



September 12, 7.50 a. m 



15 



Sheep 506 



Sheep 506 



Sheep 509 



Sheep 437 



1919. 



Sheep 372 



Sheep4(31 



Sheep 522 



Sheep 522 



Sheep 534 



Sheep 542 



September 11, 4.15 p. m 



September 12, 9.30 a. m 



17 



September 20, 5.05 p. m 



September 21, 3.18 p. m 



22 



June 22, 11.10 a. m. to (?) 



June 2.3, 8.30 a. m.. : 



September 17, 7.40 a m 



21? 



September 16, 4.25 p. m 



15 



September 10, 6 p. m 



September 11, 8 55 a m. . 



15 







i3i 



September 11, 6.55 r>. m 



September 12, 8.40 a. m 



13a 



September 22, 5.18 p. m 



September 23, 7.40 a. m 



14J 



August 30, 6 30 p m 



August 31, 7 40 a m. . 



13} 







12i 









It may be seen from the table .that in 1918 it was about 14 hours 

 after the horse had finished eating the plant before symptoms 

 appeared. 



In the feeding of the horse in 1919 it is not known when the feed- 

 ing was completed, but apparently the symptoms of intoxication ap- 

 peared in a shorter time. 



Steer 760 was fed the first time about 12.05 p. m., and the first 

 symptoms were noted about 9.13 a. m., the next day, a period of 21 

 hours. No note was made, however, of the time when the steer fin- 

 ished eating the plant, and it may be assumed that the period before 

 evidence of intoxication was not more than 18 or 19 hours. At the 

 second feeding there were symptoms in 15f hours after the feeding 

 was finished. 



In the case of sheep, information is lacking in regard to the in- 

 cipience of symptoms in Nos. 468 and 475 ; it is not known when the 

 feeding of No. 509 was completed. In regard to 14 sheep, however, 

 notes were taken of the time when symptoms v^^ere first manifest. In 

 these cases an average of the lapse of time between the feeding and 

 the symptoms is 14.1 hours. The shortest time was 2^ hours, in the 

 case of No. 480, and the longest was 22 hours, in the case of No. 506. 

 With the exception of Nos 476 and 480 all the cases lie between 15 

 and 22 hours. 



One would naturally suppose that the larger diases would take 

 effect in the shorter time, and an examination of the cases shows 

 that this is true. 



EFFECT OF REPEATED DOSES. 



The repeated feedings which were given to several of the animals 

 show significant results in regard to the questions of tolerance, in- 



