THE WHOELED MILKWEED AS A POISONOUS PLANT. 



35 



creased susceptibility, and accumulation. Following is a tabulation. 

 of repeated feedings : 



Table 4. — List of repeated feedings and results. 



■Animal. 



Steer 750... 

 Horse 126. . 



Sheep 478.. 



506.. 



Sheep 509. 



Sheep 470. 

 Sheep 470. 

 Sheep 470. 

 Sheep 470. 



Date of 

 feeding. 



1918. 

 f Aug. 22 

 I Aug. 25 

 1 Aug. 26 

 (Sept. 22 

 /July 30 

 \Sept. 20 

 June 19 

 Aug. 19 

 Aug. 28 

 Aug. 29 

 Sept. 2 

 Sept. 5 

 Aug. 26 

 Sept. 11 

 Sept. 12 

 Sept. 16 

 Sept. 18 

 Sept. 20 

 June 20 

 June 21 

 June 22 

 July 2 

 July 3 

 July 4 

 July 5 



Quantity fed 





per 100 pounds 



Result. 



of animal. 





Pound. 





0.22 



Not sick. 



.626 



Do. 



.845 



Very sick. 



.551 



Death. 



.22 



Very sick. 



.140 



Not sick. 



.165 



Do, 



.110 



Do. 



.138 



Do. 



.138 



Do. 



.147 



Do. 



.167 



Sick. 



.132 



Not sick. 



.148 



Symptoms. 



,151 



Not sick. 



.160 



Do. 



.172 



Do. 



.184 



Death. 



.189 



Not sick. 



.22(ate0.2) 



Do. 



.22(ate0.24) 



Death. 



.0473 



Not sick. 



.0473 



Do. 



.0558 



Do. 



.055 



Do. 



Animal. 



Sheep 470. 

 Sheep 470. 

 Sheep 470. 

 Sheep 470. 

 Sheep 470. 

 Sheep 470. 

 Sheep 470. 

 Sheep 470. 

 Sheep 470. 



Sheep 522. 

 Sheep 522. 

 Sheep 522. 

 Sheep 522. 

 Sheep 522. 

 Sheep 522. 

 Sheep 522. 

 Sheep 522. 

 Sheep 522. 

 Sheep 522. 

 Sheep 522. 

 Sheep 522. 

 Sheep 522. 

 Sheep 522. 



Date of 



feeding. 



1918. 



July 



6 



July 



7 



July 



8 



July 



9 



July 



10 



July 



11 



July 



12 



July 



13 



July 



14 



1919. 



Aug. 



11 



Aug 



14 



Aug. 



16 



Aug. 



IS 



Aug. 



20 



Aug. 



23 



Aug. 



25 



Aug. 



27 



Aug. 



29 



Sept. 



1 



Sept. 



6 



Sept. 



9 



Sept. 



11 



Sept. 



22 



Quantity fed 



per 100 pounds 



of ammal 



Pound. 

 0.0473 

 .0473 

 .0473 

 .05 

 .05 

 .05 

 .05 

 .05 

 .05 



.142 



.155 

 ,162 

 .169 

 ,176 

 ,183 

 .191 

 .198 

 .204 

 .219 

 .247 

 .275 

 .198 

 .147 



Result. 



Not sick. 

 Do. 

 Do. 

 Do. 

 Do. 

 Do. 

 Do. 

 Do. 

 Do. 



Do. 



Do. 



Do. 



Do. 



Do. 



Do. 



Do. 



Do. 



Do. 



Do. 



Do. 



Do. 

 Symptoms. 

 Sick. 



Sheep 470, from July 2 to July 14, was fed a daily ration of from 

 0.05 to 0.0558 pound, receiving in the whole period a total of 0.6473 

 pound, with no resulting ill effects. 



So far as cumulative effect is concerned, the 5 sheep and Steer 750 

 are the only animals that would have any bearing on the question. 

 Sheep 470 received in 15 days about four times the toxic dose with 

 no eft'ect. Sheep 478, in addition to the feedings of June 19 and 

 August 19, received on August 28 and 29 and September 2 doses 

 equal to that which proved fatal for No. 483, yet on September 5 it 

 was poisoned by an average dose, which was practically like that 

 given on June 19 with no result. 



In the case of Sheep 506, which on September 11 showed symptoms 

 from 0.148 pound, slightly increased doses on September 12, 16, and 

 18 produced no results, and death was caused on September 20 by 

 0.184 pound. 



Sheep 609, which was not affected by 0.2 pound on June 21, was 

 killed the next day by 0.24 pound, which is probably close to the 

 toxic or lethal dose for the plant as eaten by a sheep. 



Sheep 522, besides having received three feedings of marc, was 

 given 14 feedings between August 11 and September 22 of quantities 

 varying from 0,142 pound to 0.275 pound. All the feedings except 

 the last were of material from Palisades, Colo., which, as shown else- 

 where (p, 37), was less toxic than that from other localities. On 

 September 22 it was made sick by 0.147 pound of leaves from B-ock- 

 ville, Utah. 



