22 BULLETIN" 405, U. S. DEPARTMENT OF AGRICULTURE. 



her feet and then tried to walk, but was unable to stand, and lay down 

 again. At 10.47 a. m. she was unable to get her breath and went into 

 a spasm, in which her legs straightened out very much as though she 

 had been poisoned by strychnin. At 10.48^ a. m. she was breathing 

 again more naturally. She lay upon her side, trembhng violently, 

 with her hind legs extended rigidly. At 10.50 a. m. she was quiet 

 again. At this time she appeared to be a httle bloated. At 10.52 

 a. m. the muscles were rigidly contracted again, and the trembling 

 became inore violent; this was followed by a spasm, in which she had 

 great diflB.culty in getting her breath. At 10.55 a. m. she quieted 

 down again, and her respiration became more regular and deep. At 

 10.56 a. m. another spasm came on. At 10.58 a. m. she was quiet 

 again, with pulse 174, strong, and regular. At 11 a. m. another spasm 

 came on, but the animal soon became quiet. At 11.08 a, m. the head 

 was thrown back, the heart fluttered, respiration stopped, and at 

 11.10 a. m. the animal was dead. For several minutes before death 

 the heart actidn was weak, and just before death she was unable to 

 get her breath. The muscles gradually relaxed, the head was drawn 

 back, and the heart stopped. 



An autopsy was made upon the animal immediately, but very little 

 abnormal was found. The heart stopped in systole, and the brain 

 and spinal cord were congested. Other than this the animal appeared 

 to be normal. 



TYPICAL CASE OF SHEEP NO. 201. 



Sheep No. 201, a ewe weighing 71 pounds, was brought into the 

 corrals for feeding on August 16, 1913. On August 17, at 9 a. m., she 

 was given 100 grams of ripe dry lupine seeds of Lupinus leucopsis, the 

 seed having been ground in a coffee mill and mixed with 100 grams 

 of bran. At 9.30 a. m. this material had been eaten, and she was 

 given 100 grams more of the ground lupine seed, mixed with bran as 

 before. At 12.20 p. m. most of this material had been eaten. Her 

 respiration was loud and deep, as in a sleeping animal. It was esti- 

 mated that the animal had eaten altogether 175 grams of lupine seed, 

 which would be the equivalent of 0.542 pound per 100 pounds of 

 animal. 



On August 18, at 7 a. m., the animal appeared drowsy and sleepy. 

 At 7.15 a. m. she walked about a little, throwing the forelegs out 

 and dropping them as though lacking control. She staggered a 

 Httle as she walked and appeared more sleepy than an hour earlier. 

 There were some contractions of the surface muscles of the body. 

 Plate II, figure 1, shows the condition of the animal at this time. At 

 8.15 a. m. she was still upon her feet and able to walk aroimd, but 

 walked as though tipsy. When standing she appeared sleepy, the 

 ears drooped, and the eyes were half closed. She stood with her legs 

 bent at the knees and hocks. At 9.12 a. m. she still stood with the 



