THE PHILIPPINE 



Journal of Science 



B. Medical Sciences 



Vol. IV FEBRUAKY, 1909 No. 1 



ATOXYL IN THE TREATMENT OF MALARIA. 



By J. J. Vassal. 



{From the Pasteur Institute, Nhatrang, Annam.) 



In the native hospital of Nhatrang, I had the opportunity of studying 

 the therapeutical action of atoxyl on seventeen different cases of malaria. 

 The patients were Annamese and came from the gangs of workers on 

 the railway line Phanrang-Nhatrang, now in construction. There is 

 much severe malaria among them. During the two years employed in 

 the construction of the earthworks the following cases occurred: 



Cases treated. 



In hospital 



Outside hospital. 



1906. 



152 

 6,286 



1907. 



132 

 974 



The inequality in the figures is due to the fact that the workmen were 

 more numerous during the first year than the second. The Annamese 

 do not like being sent to the hospital and it is very difficult to keep 

 them there for any length of time. Therefore our observations were 

 difficult to pursue and in some cases were not carried out as thoroughly 

 as we could have wished ; some of them were even interrupted abniptly. 



Atoxyl is enjoying a vogue in therapeutics which is almost without 

 example. It has rapidly become the specific agent in sleeping sickness 

 (Thomas, Laveran, Mesnil, NicoUe and Aubert, and E. Koch) and plays 

 a prophylactic role of the highest importance in syphilis (Metchnikoff 

 and Salmon.) Its action is again manifest on several forms of trypano- 

 somiasis (Nicolle, Mesnil, Moore, Nierenstein and Todd) ; in acquired 



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