142 EDITORIAL. 



has pointod out, we know iiotliing as yet. of the morphology of the leprosy 

 bacillus on artificial media. However/ it must be admitted that the 

 changes in morphology between the organism be has cultivated and the 

 leprosy bacillus as seen in the lesions are greatei- than those seen between 

 the tubercle bacillus as it occurs in the tissues and in sputum, and in 

 cultures. 



In order for us definitely to be sure that the acid-fast organism which 

 he has cultivated is Bacillus Icprce, these experiments must be repeated 

 many times with different strains of ama?ba; and Mith numerous cases of 

 leprosy. 



Inoculations of animals with the organism will probably throw little 

 light on the subject, for while it has been occasionally possible upon 

 subcutaneous inoculation of the leprosy bacillus into monkeys, to cause 

 it to multiply slightly, a fact recently called attention to by Nicolle and 

 confirmed by Mr. Clegg in some of his early experiments, the results of 

 such inoculations are too uncertain and the lesions produced too in- 

 definite for them to be of much value in the identification of the organism. 



It would appear that Mr. Clegg has actually cultivated the leprosy 

 bacillus, but even if it should be shown in his further experiments that 

 this is not the case, his discovery will nevertheless be of importance, since, 

 if the organism is not really Bacillus leprce, it is evidently a hitherto 

 undiscovered one. 



Mr. Lindquist of Manila, P. I. : During the past week I have isolated 

 from the stools of a child an acid-fast bacillus which can be cultivated 

 on agar. I have just obtained a pure culture of this organism and I 

 will be glad to send the culture to Dr. Strong. 



Dr. Victor G. Reiser, Director of the Bureau of Health, professor of 

 hygiene, and passed assistant surgeon, Public Health and Marine-Hospital 

 Service: 1 was particularly interested in the treatment discussed by Dr. 

 Rogers, and will give his method a trial at the San Lazaro Cholera 

 Hospital as soon as the opportunity offers. The figures were very strik- 

 ing, but further confinriation seems highly desirable. 



A representative from the Pasteur Institute came here a few years ago 

 who had treated with a cholera serum, about 30 cases of cholera in Saigon 

 without a single death, but here the use of the serum at the San Lazaro 

 Hospital administered by himself, proved to be no more efficacious than 

 the routine treatment. 



Dr. Strong: 1 was also very much interested in Major Eogers's paper, 

 and I thoroughly agree with him that the replacement of the lost fluid 

 must be the primary consideration in the treatment of the collapse stage 

 of Asiatic cholera. Gartner and Beck in 1893 after experiments upon 

 dogs and rabbits, suggested the employment of a hypertonic solution of 

 sodium chloride by intravenous injection, for the treatment of Asiatic 

 cholera in order to prevent exudation from the blood into the intestinal 



