886 RUEDIGER. 



appears to Ijo more severe and larger doses of sei'iun may Ite required to 

 save the life of tlic animal. (Chart. T^o. (i.) 



Altliono'li the aceompanying charts show a mon; severe reaction after 

 the lai'ger dose of virulent hlood, the severity may have been due to otlier 

 causes, such as individiial susceptibility of the animals, difference in the 

 ])otency of the serum or difference in the virulence of the hlood employed. 



MANAGEMENT OF TJIK SERUM STATION. 



The methods of immunizing cattle, bleeding them and bottling the 

 sei-um have already been discussed. One other matter of no small im- 

 portance is the isolation and care of the non-immune cattle which are to 

 be used for virulent blood. One who is familiar with cattle plague 

 understands readily the ease and rapidity with which this disease spreads. 

 The non-immune animals must be quartered some distance from the 

 infected herd, preferably in a stable screened to keep out the birds and 

 flies which might carry the infection. Persons taking care of the animals 

 should not go near those sick nor should they touch the utensils used 

 around them ; and the feed and water of the animals must not become 

 soiled with the discharges. There must be no surface drainage from 

 the sick toward the non-immune animals. The stable should be well 

 constructed and kept in a sanitary condition in order to facilitate dis- 

 infection after an accidental outbreak of cattle plague. 



Besides the apparatus necessary for the preparation of anticattle- 

 plague serum, equijunent for microscopic and bacteriologic work is 

 necessary. 



