52 CHAMBERLAIN, VEDDER, AND WILLIAMS. 



such as arginin, histidin, asparagin, and various amino-acids ; 

 lipoids of the lecithin group and cholin; extract of onions. 



4. The neuritis-preventing principle is insoluble in ether. 



5. The neuritis-preventing principle is adsorbed by animal 

 charcoal and the filtrate through the charcoal will not prevent 

 neuritis. After adsorption the active principle can not be re- 

 moved from the charcoal by maceration with water, absolute 

 alcohol, or ether. 



6. The administration of large quantities of sodium chloride 

 failed to produce oedema in fowls suffering from polyneuritis. 



7. Five cubic centimeters of our extract (equivalent to 5 

 grams of rice polishings) is sufficient to protect fowls subsisting 

 upon polished rice. Two and one-half cubic centimeters (equiv- 

 alent to 2.5 grams of polishings) is insufficient to confer com- 

 plete protection against polyneuritis. 



REFERENCES. 



(1) Chamberlain and Vedder. A Contribution to the Etiology of Beriberi. 



Phil. Journ. Sci., Sec. B (1911), 6, 251. 



(2) Chamberlain and Vedder. A Second Contribution to the Etiology of 



Beriberi. Phil. Journ. ScL, Sec. B (1911), 6, 395. 



(3) Parrozzani. Rend. soc. chim. ital. [2] 1, No. 14. Through Chem. 



Abstracts (1910), 2492. 



(4) SCHULZE. Ztschr. f. phys. Chem. (1886), 2, 44. 



(5) Chamberlain, Bloombergh, and Kilbourne. A Study of the Influence 



of Rice Diet and of Inanition on the Production of Multiple Neuritis 

 of Fowls, and the Bearing Thereof on the Etiology of Beriberi. Phil. 

 Journ. Sci., Sec. B (1911), 6, 177. 



(6) Fales. Beriberi, its Etiology and Prevention. Journ. Am. Med. Ass. 



(1907), 48, 776. 



(7) Fraser and Stanton. The Etiology of Beriberi, Studies from the 



Institute for Medical Research, Federated Malay States, No. 12, 

 page 74, 



(8) Schauman. Die ^tiologie der Beriberi unter Beriicksichtigung des 



Gesammten Phosphorstoffwechsels. Arch. f. Schiffs- u. Trop.-Hyg. 

 (1910), 14, No. 8. 



(9) Shiga und Kusama. Uber die Kakke-ahnliche Krankheit der Tiere. 



Arch. f. Schiffs- u. Trop.-Hyg. (1911), 15, No. 3. 



