ETIOLOGY OF BERIBERI. 343 



eighty-first day the note was made that the right knee jerk was 

 very active but that the left seemed a little weak. On the eighty- 

 fifth day the systolic blood pressure was 100 millimeters Hg. 

 On the ninety-fifth day the knee jerks were both active. On 

 the ninety-seventh day it became necessary to discontinue the 

 diet as he refused to continue the experiment longer. At this 

 time his condition was good, although he had lost 4.5 kilograms 

 (10 pounds) in weight. The condition of the heart remained 

 unchanged. The knee jerks were active and there was no oedema 

 of the legs, tenderness of the calves of the legs, nor areas of 

 anaesthesia of the skin. The urine was normal. 



CASE NO. 15 (GROUP Hi). 



Diet: White rice + rice polishings for 17 days") 



followed by red rice for 100 days, together 



with the special diet common to all the 



groups. 

 Dried codfish and potatoes were added to the diet on the 97th day 



Total period of experi- 

 ment, 117 days. 



Following is a summary of the notes of the case : Percussion 

 and auscultation of the lungs reveal nothing abnormal; the ex- 

 amination of the heart shows no increase in the area of cardiac 

 dulness beyond the normal; the point of maximum impulse is 

 palpable 7 centimeters to the left of the median line and 1 centi- 

 meter below the nipple line; the heart sounds are clear at the 

 apex and base; there is no epigastric pulsation; the pulse is 72 

 and the systolic blood pressure 130 millimeters Hg (Faught) ; 

 the spleen and liver are not enlarged ; the knee jerks are active. 



The earlier notes of this case show no important changes in the 

 condition of the individual except that he lost weight gradually 

 up to the seventy-seventh day of the experiment when he 

 weighed 4.5 kilograms (10 pounds) less than when the experi- 

 ment was begun. On the eighty-first day the systolic blood 

 pressure was 100 millimeters Hg. On the ninetieth day the 

 note states: He has eaten little for two days and complains of 

 headache ; there are no cardiac symptoms ; his headache and loss 

 of appetite were relieved by purgation; the knee jerks have been 

 active throughout. On the ninety-seventh day dried codfish 

 and potatoes were added to the diet. On the ninety-ninth day 

 the following note was made : No throbbing over cardiac area ; 

 pulse 80; point of maximum impulse invisible; palpable within 

 the nipple line; heart sounds clear and slightly accentuated at 

 the base; the knee jerks are active; no increase in the cardiac 



