402 



STRONG AND CROWELL. 



but the potatoes only 0.25 per cent, which is less than the 

 amount present in the white polished rice (0.37 per cent) em- 

 ployed in the experiments. The loss of weight in the subjects 

 comprising this group, during the experiment, was as follows: 



Group I. 



Case. 



Lost- 



Then gained- 



Kilograms. 



Equivalent 

 in pounds. 



Kilograms. 



1 

 Equivalent 

 in pounds. 



No. 1 « 



7.9 



2.9 



4.5 



2.04 



2.04 



4.3 



17.5 

 6.5 



10.0 

 4.6 

 4.5 

 9.5 







No. 2 







No. 3« 







No. 4 



No. 5 







2.9 



6.5 



No. 6 









» Developed symptoms of beriberi. 



In none of the other cases of this group was the loss of 

 weight so marked as in case No. 1, though case No. 6, in which 

 no symptoms of beriberi developed, lost practically as much (4.3 

 kilograms or 9.5 pounds) as did case No. 3. 



In Groups II and IV the diet consisted largely of white rice. 

 In Group II, 4 of the 6 individuals comprising the experiment 

 developed beriberi (Nos. 8, 9, 10, 11) and 2 (Nos. 7 and 12) 

 early symptoms of the disease, while in Group IV, 4 of the 11 

 (Nos. 20, 26, 25, 29) developed beriberi, 2 (Nos. 19 and 22) 

 developed early symptoms of the disease, 1 (No. 21) doubtful 

 symptoms, and 3 (Nos. 24, 27, 28) showed no symptoms of 

 beriberi throughout the experiment. 



It is also advisable to examine into the symptoms of beriberi 

 which developed in the individuals comprising these groups. In 

 case No. 8 of Group II the most striking symptoms were the 

 oedema of the legs and tenderness of the calf muscles, loss of 

 knee jerks, and change in the position of the apex beat of the 

 heart. In case No. 9, epigastric pain and pulsation, marked 

 dyspnoea, parsesthesia and hypersesthesia of areas of the skin, and 

 hyperaesthesia of the muscles of the calves, together with loss 

 of knee jerks. In case No. 10 the prominent symptoms were 

 cardiac disturbances, hypersesthesia of the calf muscles, and 



J 



