ETIOLOGY OF BERIBERI. 



Group HI. 



405 



Case. 



Lost- 



Then smined— 



Kiloirrams. 



Equivalent 

 in pounds. 



Kilotrrams. 



Equivalent 

 in pounds. 



No. 13" 



No. 14 



6.8 

 4.8 

 6.2 

 2.4 

 8.6 

 2.4 



16.0 

 9.6 



11.6 

 6.6 

 8.0 

 6.6 









No. 16 







No. 16 



2.0 



2.0 



4.6 

 4.6 



No. 17 



No. 18« 









» Developed symptoms of beriberi. 



From an examination of the tables showing the loss of weight 

 in the patients in the four groups, it is seen that in some in- 

 stances the loss of weight in those individuals who developed 

 beriberi was marked, for example. No. 8, 4.5 kilograms (10 

 pounds) ; No. 9, 6.1 kilograms (13.5 pounds) ; and No. 26, 7.4 

 kilograms (16.5 pounds). In other cases, Nos. 10, 20, and 25, 

 it was slight, 6, 6, and 8 kilograms, respectively, while in the 

 most acute case. No. 29, there was no loss of weight at the end 

 of sixty-one days when the patient died. 



Cases Nos. 1 and 3 of Group I lost more in weight than any 

 other members of the group, namely 7.9 and 4,5 kilograms (17.5 

 and 10 pounds), respectively, and were the only members of the 

 group that developed symptoms suggestive of beriberi. No. 1 

 developed much more marked symptoms than No. 3. However, 

 case No. 6 of the same group lost 4.3 kilograms (9.5 pounds) 

 and developed no symptoms of the disease. Case No. 13 of 

 Group III lost 6.8 kilogi'ams (15 pounds) in weight, more than 

 any other member of the group, and was the only one of the 

 group to develop striking symptoms of beriberi. But case No. 

 7 of Group II developed no symptoms of beriberi and lost 6.1 

 kilograms (13.5 pounds), and case No. 21 of Group IV lo.st 6.8 

 kilograms (15 pounds) in the earlier part of the experiment, 

 and also developed no symptoms of the disease. Apparently, 

 therefore, the development of the symptoms of beriberi did not 

 necessarily occur in at least all of these cases on account of the 

 loss of weight, though it is certainly suggestive in cases No. 1 

 of Group I and No. 13 of Group III that there might be some 

 connection between the loss of weight and the development of 



