THE PHILIPPINE 



Journal of Science 



B. The Philippine Journal of 

 Tropical Medicine 



Vol. VII OCTOBER, 1912 No. 5 



A STUDY OF polyneuritis GALLINARUM." A FIFTH CON- 

 TRIBUTION TO THE etiology OF BERIBERL 



By Edward B. Vedder and Elbert Clark.' 



CONTENTS. 



I. Observations on Symptomatology. 

 II. Observations on Pathology. 



III. Observations on the Earliest Degenerative Changes in the Nerves. 



IV. The Influence of Various Articles of Food on the Production of Poly- 



neuritis Gallinarum. 

 V. Summary. 

 VI. Conclusions and Discussion. 



Since Eijkman(i) first described polyneuritis gallinarum a 

 large number of investigators have studied this disease. At the 

 present time there is general agreement among these investi- 

 gators that the disease is produced by an exclusive diet of pol- 

 ished rice and may be prevented and cured by the addition of 

 rice polishings or various extracts of rice polishings to the 

 diet. Some of these investigators (2) (3) (4) described briefly the 

 symptomatology and pathology of the disease, but the majority 

 have confined themselves to the study of its etiology. 



* Read before the Philippine Islands Medical Association, November, 

 1912, and published with permission of the Chief Surgeon, Philippine 

 Division. 



' Edward B. Vedder, captain, Medical Corps, United States Army, 

 member of the United States Army Board for the Study of Tropical Diseases 

 as they Exist in the Philippine Islands. 



Elbez-t Clark, associate professor of anatomy, University of the Philip- 

 pines. 



'The experimental work is by Vedder; the microscopic work by Clark. 

 114707 " 423 



