official inspections 48. 27 



Preparinc, and Keeping Sweet Spirit of Nitre. 



If spirit of nitrons ether is prepared, kept and dispensed in 

 accord with the following directions that were published in 1908 

 by the Executive of the Drug Law it will be of perfect strength. 



Concentrated nitrons ether. Purchase concentrated nitrous 

 ether from a reliable house. If the label does not carry the U. 

 S. serial number, obtain a written guaranty from the seller as 

 to its strength. 



Buy in small sealed packages so that the spirit of nitrous 

 ether made therefrom will under ordinary conditions be sold 

 inside of one month.* 



Preparing spirit of nitrous ether. This may be prepared ac- 

 cording to the U. S. P. Eightli Edition or may be made from 

 concentrated nitrous ether. 



If the latter method is used, follow directions for preparation 

 as given by the manufacturer as regards the proportions of 

 concentrated nitrous ether and alcohol to be used. 



Thoroughly chill both the concentrated nitrous ether and 

 the alcohol. I.^se a towel or other nonconducting material in 

 handling the concentrated nitrous ether container. Do not pour 

 t/.rough the air more than absolutely necessary. 



Keeping spirit of nitrous ether. Store in small, amber colored, 

 glass bottle, stoppered with tight fitting cork stopper. Do not 

 use a ground glass stopper. 



Keep the bottle in a cool place. Room temperature is not cool 

 enough. 



Put the date of manufacture on the bottle. 



Do not sell after six weeks from preparation without testing 

 strength by assay. If weak bring up to strength by adding con- 

 centrated nitrous ether q. s. and put new date on bottle. 



Put date 01 manufacture on bottle given to customer. 



* Concentrated nitrous ether in small-sealed tubes or other packages 

 may be purchased and when added to one pint of alcohol will make 

 a trifle more than one pint of spirit of nitrous ether of U. S. P. strength. 



