EFFECTS OF TUBERCULIN ON TUBERCULOUS COWS. 163 



As noticed in the report for 1896, we see that the animals 

 slightly affected with tuberculosis when tested with tuberculin 

 failed to react oftener than they reacted, and the reactions seem 

 to bear no relation to the length of time intervening between 

 tests. The first of the animals killed was Dunkard Girl. When 

 she was killed January 15, 1897, she had been diseased nearly 

 a year and a half, yet the disease had made little advance. She 

 had never exhibited any physical signs of disease. At the time 

 she was killed she was decidedly fat. Two guinea pigs inocu- 

 lated from her died with tuberculosis. 



February 27, 1897, Ruth C. was killed. It had been over 

 six months since she had reacted. But she had been coughing 

 to a noticeable degree for more than a year, and had not been 

 as thrifty as the rest of the herd. How much of this lack of 

 thrift was due to her diseased condition is uncertain as she 

 apparently belonged to rather a frail type before she gave evi- 

 dence of disease. The autopsy revealed only a small area of 

 diseased lung and two enlarged lymphatic glands. 



June 17, 1897, Grace was killed in an advanced stage of 

 tuberculosis. When she calved April 24, 1897, she was in good 

 flesh and apparently perfectly well, and she did well at the time 

 of calving, but very soon afterwards it was noticed that she was 

 rapidly losing flesh and she manifested other marked symptoms 

 of tuberculosis, including a severe cough, rough coat, irregular 

 appetite, and considerable fever. Her temperature was taken 

 frequently and was rarely found below 104 and was often above 

 105 . An examination of the lungs ten clays before she was 

 killed revealed the fact that they were considerably diseased. 

 She had some appetite and considerable strength at the time 

 she was killed. At the autopsy a very large number of tuber- 

 cles, varying in size from a pin head to three inches in diameter, 

 were found scattered through both lungs, and attached to both 

 the parietal and visceral pleura. The bronchi contained much 

 frothy mucus. The mediastinal lymphatic glands were 

 enlarged and much congested. The tubercles presented no 

 evidence of degewerative changes. She had not been tested 

 since she calved. Her temperature had been constantly high. 



