60 



SELLARDS AND SHAKLEE. 

 Table VI. — Injection of sodium hicarbonate. 



Interval 

 between 

 speci- 

 mens. 



Cubic 

 centi- 

 meters of 

 urine. 



Per cent 

 of urea. 



Hours. 



15 

 6 

 2 



0.05 

 0.05 

 0.05 



6i 



8 



Grams 

 of urea. 



0. 0075 

 0.003 

 0.001 

 Injection of 30 grams sodium bicar- 

 bonate. 



0.15 

 0.55 

 1.2 

 2.86 

 3.00 

 2.88 

 Eecovery. 

 I 



4 



300 



0.05 



21 



110 



0.5 



1 



150 



0.8 



Ij 



220 



1.3 



3 



200 



1.5 



4 



240 



1.2 



This might be interpreted as indicating that until the alkali was 

 injected, nitrogenous material was being utilized for the neutralization 

 of acids. However, there is one step in this explanation which is not 

 clear. If the nitrogen neutralizes acids, one would expect to find ammo- 

 nium salts in the urine on testing with sodium hypobromite, unless the 

 neutralization took place in such a way that the resulting product failed 

 to be excreted in the urine, or perhaps failed to react with the evolution 

 of gas in the presence of the h3rpobromite. 



For convenience, the results of the injections of urea and of sodium 

 bicarbonate have been plotted in the accompanying charts. One of the 

 urea cases (number 15) has been omitted as the data were incomplete. 

 In two cases (numbers 11 and 18), the specimens of urine which were 

 necessary for quantitative results could not be obtained; the qualitative 

 changes, although somewhat suggestive, are not conclusive. The chart 

 from Table II (case number 4) is especially interesting. Here the urea 

 content following the injection of urea, rises from 0.1 to 1.8 per cent and 

 then returns rapidly to its original point. The chart corresponding to 

 Table VI gives the effect of the injection of sodium bicarbonate. Here 

 the urea content rises from almost zero to normal and continues a normal 

 course. In the control case, the amount and per cent of urea remain con- 

 stantly low. 



