72 



SELLARDS AND SHAKLEE. 



The results, with the two groups of cases, showed that with Einger's 

 solution, onh' a small percentage of cases recovered after more than 

 one day of anuria. In the bicarbonate group, a number recovered after 

 one day of complete suppression of urine. The data are as follows : 



Treatment. 



Duration of anuria. 



Less than 

 24 hours. 



24 to 48 

 hours. 



Ringer's 



Bicarbonate, 



10 

 10 



In dividing the patients into two similar groups, both the severity of 

 the cholera symptoms and the general physical condition of the pa- 

 tients were considered. As nearly as could be determined there was 

 no difference in either direction in the severity of the two series. The 

 group treated with serum and bicarbonate represents those cases which 

 went into complete collapse and in whom the symptoms of toxaemia were 

 more or less prominent. Of the fifteen individuals treated with bicar- 

 bonate alone, five, and of the twenty-two control cases, twelve, were 

 admitted in complete collapse. 



The following classification has been iised for estimating the effect of 

 the bicarbonate solutions on the cause of death. Under collapse and en- 

 teritis are included those cases which die primarily from loss of fluid 

 and also those which continue to live until the enteritis with its accompa- 

 nying toxsemia is well developed. The urgemia of cholera, while differing 

 from that of ordinary nephritis, is nevertheless characteristic. Two cases 

 occurred in which symptoms both of uraemia and of the toxsemia of the 

 cholera infection were present. Since each of these conditions may have 

 been contributing factors in the cause of death, these are recorded as "in- 

 termediate." 



The final results are given in the accompanying outline. , 



Treatment. 



Num- 

 ber of 

 cases. 



Cause of death. 



Total 

 number 



of 

 deaths. 



Total 



number 



of 



recov- 

 eries. " 



Col- 

 lapse. 



Urae- 

 mia. 



Inter- 

 medi- 

 ate 

 cases. 



Bicarbonate and serum* 



Bicarbonate 



Total with bicarbonate 



Control with Ringer's 



7 

 15 



3 

 1 







3 



1 



4 

 14 











22 

 22 



4 

 •5 







1 

 9 



18 

 13 



2 



2 





■ Including one patient receiving normal serum. 



