448 



4. From one of the halones, about a quarter oi an inch ex- 

 ternal to the germinal centre, I took a fragment, which, when 

 submitted to a power of 900 D., presented the following ele- 

 ments : 



a. Large flat masses of a finely granular base or stroma, 

 with superposed free granules, small vesicles, and oil-globules. 



b. A considerable number of long flat bands or fibres, with a 

 very fine, clear, double outline, and minutely granular centre, 

 and occasional superposed and adjacent small vesicles and gra- 

 nules; here and there a small vesicle was to be found lying 

 partly within and partly without the fibre. In some places 

 the fibres appeared to me to terminate by tapering, indistinct 

 granular ends, and I am much disposed to think that this in- 

 dicates the true mode of their formation, viz., by the linear 

 aggregation of granules. On the addition of acetic acid, I 

 could get no indication of nuclei, or of the outlines of cells of 

 any kind. 



c. The large vesicles still exist in abundance, but I cannot 

 see them anywhere to be distinctly engaged in forming any 

 structure ; I have looked in vain for nuclei in them ; there 

 appear to be two varieties of them — one finely granular, the 

 other containing numerous large, dark globules. I think they 

 become larger and more numerous for a certain time, and then 

 break up ; I look upon them as a-plastic, and consider their 

 most probable use to be that of forming loci for the chemico- 

 molecular elaboration of or change of combination of the 

 chemical elements. The fibres above alluded to were found 

 in the vicinity of granules, granular masses, and a small va- 

 riety of cells. 



5. In a preparation from near a blood islet I obtained a 

 number of reddish-coloured elliptical corpuscles, some with 

 nuclei, others without, also large finely granular vesicles, and a 

 smaller kind of hyaline clearness, which burst on the addition 

 of water. 



6. In the plasma from a cut in my finger, five minutes after 



