442 WALLACE LARKIN CHANDLER 
Observations: The animal remained fairly quiet during the fumigation 
and was removed from the tank at 5.25 p. m. in an apparently normal 
condition. It was lively, ate heartily, and showed no symptoms of poison- 
ing. No symptoms developed during the next three days. 
January 8 — When seen at 11 a. m. the animal was apparently well and 
normal. At 5 p. m., however, it exhibited a loss of coordination of the 
muscles of the hind legs, and had vomited at some time previously. At 
8 p. m. it was unable to stand. 
January 9— The animal was found lying on its left side in a helpless 
condition; when placed on its right side, it struggled violently until it 
regained the left side; it refused cooked meat and water, but drank a 
little milk. At 12 m. nystagmus was observed; the pupils were normal; 
the animal ate a little cooked liver. By 3 p. m. nystagmus was very 
marked; the pupils were normal; knee-jerk reflex was good in both legs. 
When seen at 7 p. m. the animal tried to stand on its feet, but its hind 
legs were apparently paralyzed; when it did not succeed, it at once 
began to howl. 
January 10 — The condition of the animal was about the same. It lay 
continually on its left side and was unable to move its body. There 
was a certain amount of rigidity of the leg muscles at times, but this 
was not well marked. Knee-jerk reflex was good. The animal ate 
cooked meat, and drank milk but no water. Nystagmus was not notice- 
able. 
January 11 — The condition of the animal was slightly improved. It 
could move its legs a little. It ate meat and drank milk, but refused 
water (it was given meat and milk twice). The pupils were normal. 
January 12 — The condition of the animal was much improved. It was 
able to lift its body on its fore legs and crawl about the cage, but the 
fore legs weakened quickly. The animal passed urine which was very 
dark. It ate meat greedily and drank some water. 
January 138 — The condition was much improved. The animal was able 
to walk about very well, but its legs seemed weak and gave way at 
times. 
January 14 — The condition was still further improved. 
