PuystroLocicaLt Action or NrtRoBENZENE VAPoR ON ANIMALS 443 
January 15—The condition was apparently normal. The dog was 
turned loose with the other dogs. 
In this case no definite convulsions were observed, the dominant 
symptom being paralysis such as was reported by Filehne as following 
a slow action of the drug. 
DOG XVIII (FEMALE) 
Weight of dog, ? (small, rather thin; heavy Demodex infection). 
April 23, 1917 — Dog fumigated at 23° C. for a period of four hours. 
Time when fumigation was begun, 2 p. m. 
Time when fumigated was finished, 6 p. m. 
Observations: The animal was restless for a time after being placed 
in the fumigation chamber, but soon became quiet. It was removed 
apparently unharmed, and never developed any symptoms of poisoning 
as the result of this fumigation. 
May 16, 1917 — Dog fumigated a second time, this time at 20° C. for a 
period of five and one-half hours. (The dog was slightly fatter than 
when first fumigated.) 
Time when fumigation was begun, 1.10 p. m. 
Time when fumigation was finished, 6.40 p. m. 
Observations: As before, the animal was a bit restless when first 
placed in the tank, but it soon became accustomed to its new environment 
and became quiet. It was removed from the tank apparently unharmed, 
showing no signs of nitrobenzene poisoning and drinking water freely. 
May 17 — No symptoms had developed. 
May 18 — The animal was found with its hind legs paralyzed, and there 
were evidences of its having thrashed about during the night. It 
drank milk and water freely and ate meat. It was placed in a padded 
cage. 
May 19— The general condition of the animal was worse. It could 
raise its head and wag its tail, but its legs were useless. It ate and drank. 
This condition remained about the same until May 22, when some improve- 
ment was noticed. 
