446 WaLLAcE LARKIN CHANDLER 
from the tank and was found to be in a stupor; it was wholly relaxed and 
perfectly reactionless. It remained in this condition for a few hours, 
and then died, without any signs of convulsions. 
GRAY RATS 
(Mus decumanus) 
Five young rats were placed together in a large wooden box having a 
capacity of 10 cubic feet. Fifteen drops of nitrobenzene were placed on 
a strip of cheesecloth and the cloth was suspended in the box, which was 
then closed for twelve hours. At the end of that time the rats were 
removed. The animals were all perfectly anesthetized, and three of 
them were reactionless. One died five hours later, and another was 
killed for the purpose of examining its blood; both of these had dark 
brown blood. All the other three exhibited either right or left rotatory 
(pinwheel) movements; one of them was seen to roll over and over for 
several feet before becoming exhausted. Two of these remaining three 
died without showing other symptoms, and one recovered (at least tem- 
porarily) and escaped. 
Two adult rats of the same species were fumigated together in the 
regular fumigation chamber for three and one-half hours at a temperature 
of 23.5° C. When removed from the tank they were apparently unharmed. 
Both of these died two days later, probably from lack of nourishment 
since 1t was impossible to induce them to eat while in captivity. 
WHITE RATS 
It was found that white rats could not stand a fumigation at ordinary 
temperatures for longer than from one and one-half to two hours. How- 
ever, the rats used in these experiments were infected with trypanosomes 
and spirochetes, and this fact may have had something to do with 
hastening the action of the drug. The rats that were still alive when 
removed from the tank showed only paralysis and usually died very 
quickly. 
CAT IX 
September 26, 1916 — Cat fumigated at 17° C. for a period of five hours. 
Time when fumigation was begun, 11.50 a. m. 
Time when fumigation was finished, 4.50 p. m. 
