96 AEON. 



Experiment IV. — Weight of monkeys fed on bread and water. 



Date. 



I. 



II. 



III. 



IV. 



V. 





] , 853 

 1,324 

 1,315 

 1,287 

 1,077 

 1,079 

 1,000 

 920 

 ° S 42 



2,083 



'1,814 



2, 123 

 2, 131 

 2,087 

 2,102 

 2, 037 

 2,005 

 1 , 975 

 1,720 















1,745 

 1,722 

 1,590 

 1,480 

 1, 545 

 1,530 



1,440 

 1,447 

 1,130 

 1,400 

 1,375 

 '1,130 



February 1 















Februarv 28 . 



March 1 , 









11 1,745 



CO 













a Died January 18, stroDg diarrhoea, unknown origin. 

 h Died February 27, weakness, etc., as described below. 

 c Died March 1. weakness, etc., as described below. 

 ,l Died March 2, weakness, etc., as described below. 

 e Died March 26, weakness, etc., as described below. 



Three animals were selected at first, but one (Number II) died in the 

 beginning of the experiment of a severe diarrhoea of unknown origin. 

 Two others were taken about two weeks later. The experiment demon- 

 strated .that bread and water alone are not capable of sustaining monkeys 

 in full health for a longer period than from four to six weeks. In spite 

 of the fact that the animals ate the equivalent of 80 to 100 calories and 

 0.3 gram protein per kilo of body weight, they died in about six weeks, 

 with signs of general weakness and emaciation. The muscular weakness 

 in some of the monkeys was very prominent. The animals, which in the 

 beginning would run away if approached and if caught would resist their 

 captor with considerable muscular force, were now handled without trouble 

 and were scarcely able to hold themselves with their hands gripping the 

 arm or fingers. Death came at last, the respiration becoming slower and 

 slower, and weaker and weaker. At autopsy no pathologic changes 

 other than those incident upon emaciation and anaania were noticed. 

 The histologic examination of the nerves has not up to the present 

 been undertaken. No experiments on the action of phytin on monkeys 

 nourished in the manner outlined above were made. 



Guinea pigs will not eat white rice, either cooked or uncooked. When 

 given it they die of starvation in from two to three weeks' time. 



I attempted, but with considerable difficulty, to feed adult dogs on 

 white rice and lard. A series of experiments on young dogs will be 

 described later, in connection with other work. 



Schaumann, 13 in his latest paper, reports that he was able to produce 

 lesions of polyneuritis in dogs, cats, and rats by feeding them horse 

 meat which had been heated in a 20 per cent solution of sodium carbonate 

 for three hours. However, the full details have not as yet been published. 



