160 MCLAUGHLIN AND ANDREWS. 



However, it must be remembered that the etiology of this disease is 

 unknown. Clinically, the cases must be observed by competent men 

 under favorable conditions where a complete clinical record can be made. 

 The sick ones should be taken to a hospital where they can be studied 

 carefully and all laboratory and biologic tests applied. The careful 

 examination of all body fluids and excreta, biologically and chemically, 

 is imperative. Further, the possibility of an ultramicroscopic organism 

 must not be overlooked, neither should the internal secretions be forgotten. 

 At the same time, a thorough chemical and biologic examination of the 

 mother's milk is essential. At death a quick necropsy with complete 

 biologic examination must follow. This would also give material for 

 thorough histologic study, which has been impossible so far because of 

 post-mortem changes. 



The writers wish to extend their thanks to Dr. H. Winsor, of St. Paul's 

 Hospital, for performing some of the autopsies. 



