TREATMENT OF STRYCHNINE POISONING. 551 



a preliminary, some had both morphine and atropine, and some had 

 neither. Four of these dogs were saved from strychnine death but, 

 these four died subsequently, apparently from chloroform poisoning. 

 Two of the four had a small dose of morphine each, as a preliminary; 

 one had morphine and atropine, and the fourth had neither. 



Discussion. — A comparison of these nine eases treated with chloroform 

 with the series of eleven treated with ether \sy the writer at the Eock- 

 efeller Institute, brings out a marked difference in the results of the 

 two methods. Of the eleven dogs treated with ether only one failed 

 to make a permanent recovery, and to that one the anaesthetic was admin- 

 istered by means of a cone provided with a wad of cotton soaked with 

 ether. But of the nine treated here with chloroform none made a 

 permanent recovery. At present it hardly seems possible to improve 

 upon the treatment with chloroform as exemplified in protocol number 

 8, to a degree that will remove the danger of subsequent chloroform 

 death. 



CONCLUSIONS. 



1. Dogs poisoned with doses of strychnine which are certainly fatal 

 may recover from the effects of the strychnine if properly treated with 

 chloroform together with the intravenous injection of liberal quantities 

 of Einger-Locke solution. 



2. Better results are obtained if the chloroform is given by intra- 

 tracheal insufflation and in uniform concentration as low as consistent 

 with the condition of the patient. 



3. Dogs saved from strychnine death by means of chloroform are 

 likely to die later of chloroform poisoning. 



4. Chloroform is far inferior to ether for the treatment of strych- 

 nine poisoning, and probably for the treatment of convulsions in general. 



5. Further experiment is necessary to determine the merits or de- 

 merits of atropine and of morphine in the treatment with chloroform of 

 strychnine poisoning. 



