﻿110 



ASHBURX AND CRAIG. 



It will be observed that the eosinophils showed a marked increase as 

 the disease progressed, and this has been noticed in several of our cases. 

 While the above differential count is typical of the results obtained by 

 some observers, we have found, even in a limited number of examina- 

 tions, that it is not of sufficiently frecpient occurrence to be depended 

 upon alone in reaching a diagnosis. In fact, in most of our counts we 

 found that the small lymphocytes outnumbered the large in every stage 

 of the disease. 



Vedder, as a result of his observations upon the white blood count 

 in dengue, has submitted to us the following data. His blood counts 

 were made on patients suffering from the disease occurring in the same 

 epidemic which we have described above. 

 savs : 



Regarding his results he 



The polymorphonuclear leucocytes are greatly decreased and the small lympho- 

 cytes are greatly increased, while the large lymphocytes are moderately increased 

 during the latter days of the illness. These changes are, to a greater or less 

 degree, characteristic of the disease throughout its duration. The decrease in 

 polymorphonuclears and the increase in small lymphocytes takes place almost at 

 once, being very noticeable on the second day of the illness. 



Vedder regards the differential leucocyte count as of great value in 

 the diagnosis between this disease and yellow fever. 



The following table gives in percentages, the results obtained by Tedder 

 in five cases in which a differential count was made on each day of the 

 disease: 



CASE 1. 



Dav. 



Leuco- 

 cytes. 



Polymor- 

 phonu- 

 clears. 



Small 

 lympho- 

 cytes. 



cvtes. ; clears - 



Eosino- 

 philes. 



Xn mber. 

 5,300 

 4,100 

 5,900 

 4,400 

 4.700 

 5,250 

 4,700 

 4,800 



Per cent. 

 79. 50 

 .50.00 

 45. 00 

 46.00 

 58. 25 

 46.33 

 29.50 i 

 27.50 



Per cent. 

 16.00 

 43.00 

 48.25 

 40.25 I 

 34.00 j 

 43.33 

 56. 00 j 

 60.00 



Per c( nt. 

 2.50 

 5.50 

 5.75 



10. 75 

 6.30 

 8.66 



11. 75 

 11.25 



Per cent. 

 0.50 

 1.50 

 1.00 

 3.00 

 1.25 

 1.00 

 2.50 

 .50 



Per cent. 

 1.50 

 

 

 

 



.66 

 



.75 



CASE 2. 



1 - - . 



4.200 



2. 



3,800 

 6. 500 



3 



4 



2. 750 





2,600 



6 



4, 550 



7 



8-_ 



5, 550 



9 





60.00 

 40. 50 

 25.00 

 34.00 

 45. 00 

 23.33 

 38. 75 

 30.00 

 30.00 



17. 75 

 45.00 

 .54.33 

 44.00 

 45.66 

 48.33 

 50.00 

 47.33 

 46.66 



7.50 

 10.00 

 8.00 

 6.00 

 7.66 

 8.33 

 8.50 

 6.33 

 11.66 



2.00 

 3.00 

 2.00 

 1.00 

 1.00 



.66 

 1.75 



.66 

 1.33 



12. 75 



1.50 



10. 66 



15.00 



1.66 



19. i3 



.50 



15. 33 



10.00 



