﻿THE PHILIPPINE 



Journal of Science 



B. Medical Sciences 



Vol. II JUNE, 1907 No. 3 



STUDIES IN PLAGUE IMMUNITY.' 



By Richard P. Strong. 

 [From the Biological Laboratory, Bureau of Science.) 



CONTENTS. 



I. Introduction. 

 II. Discussion op the Prophylactics Previously Employed. 



1. Methods of preparation. 



2. Extent employed in man and results obtained. 



III. Cultures Employed in the Experimental Work. 



IV. Animals Employed — Their Susceptibility to Pest Infec- 



tion — Lethal Dose — Technique of Infection. 

 V. Immunization of Animals. 



1. With killed pest bacilli. 



2. With living attenuated cultures (vaccination). 



3. With filtered cultures and extracts (free receptors) of the organism. 



4. With plague aggressin. 



(a) Artificial aggressin. 



(b) Natural aggressin. 



5. With Klein's method. 



VI. Series of Animal Inoculations Employed in Testing the 

 Immunizing Value of the Different Methods. 

 VII. Summary of the Eesults of the Animal Experiments in Im- 

 munization by the Different Methods. 



1 Read by abstract at the Fourth Annual Meeting of the Philippine Islands 

 Medical Association March 2, 1907. 



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