﻿280 



STRONG. 



Series 19 — Continued. 



Animal 

 No. 



Serum intra- 

 peritoneal!;,-. 



How inocu- 

 lated. 



Result. 



Autopsy and remarks. 



1401 



5 cc. from 



Stuck with 



Dead alter 



No pest bacilli found in smears from the spleen 





case 28. 



infected 

 needle. 



7 days. 



or in tissues near the point of inoculation. 

 Spleen small. No infiltration about point of 

 inoculation. It is not clear that this rat died 

 of pest infection. 



1402 



4 cc. from 



do _ . 



Dead after 



Innumerable pest bacilli in smears from 





case 29. 





4 days. 



spleen. 



1403 



do 



do— _ 



Dead after 

 3 days. 



Very numerous pest bacilli in smears from 

 spleen. 







1404 



2.5 cc. from 

 case 31. 



do 



do 



Very few pest bacilli in smears from the 

 spleen. Innumerable in smears from tissues 

 near point of inoculation. 



1405 



.._ _do 



_do_ __ 



Dead day of 











inocula- 











tion. 





1406 



3.25 cc. from 



___. do 



Dead after 



Very numerous pest bacilli in smears from 





case 33. 





3 days. 



spleen. 



1407 



do. 



do 



Dead after 



Numerous pest bacilli in smears from spleen. 









4 days. 





1408 





_.do 



Dead after 



A few pest bacilli in smears from spleen. 









2 days. 





1409 





_ _ do 



Dead after 



A fair number of typical pest bacilli in smears 









4 days. 



from spleen. 



1410 





do 



Dead after 

 6 days. 



Very numerous pest bacilli in smears from 

 spleen. 



1411 





do 



Dead after 

 4 days. 



Do. 







1412 



0.5 cc. anti- 



do 



do 



Numerous pest bacilli in smears from the 





p e s t i c 







spleen. Many swollen. A few near the 





serum. 







point of inoculation. 



1413 





..._do 



Dead after 

 3 days. 



Very numerous pest bacilli in smears from 

 spleen. 







It might be argued that not a sufficient number of animals were inoc- 

 ulated in the different series with each serum for the results to be conclu- 

 sive, since it is well known that in a series of rats inoculated with a pest 

 immune serum of high value, a certain number of animals are not pro- 

 tected and always die of pest infection after inoculation with a virulent 

 organism, and indeed, the single animal of this series inoculated with the 

 horse's pest immune serum succumbed to pest. However, it seems prob- 

 able that in such a long series of animals, if there were any the blood of 

 which possessed marked anti-infectious power, the evidences of this fact 

 would be presented by at least some of the animals. Only in the serum 

 of case 28 is there any evidence whatever of an anti-infectious power and 

 there is no further evidence of this nature in any of the other series 

 of rats which have been inoculated with serum from human cases vac- 

 cinated against plague. (Compare with Series 22, p. 281 animals 1454 

 and 1455.) 



