﻿ILLUSTRATIONS. 



Plate I. 



Fig. 1. Young papule from patient with leprosy and yaws. Magnification, 95 X 1. 

 a, Edge of crust over the ulcer, composed of necrotic epithelium, leuco- 

 cytes, ^etc. b, Hypertrophied epithelium, c, Epithelial downgrowth, 

 with leucocytic infiltration, d, Base of ulcer, showing preservation of 

 deepest layer of epithelium, beginning epithelial downgrowth, and cover- 

 ing of epithelial debris, e, Downgrowth, showing preservation of the 

 columnar cell layer with degeneration of the central portion. /, /, Cap- 

 illary dilatation in the oedematous cutis. 

 2. Early papule from monkey. Magnification, 95 X 1. a, Beginning loss of 

 surface epithelium. 6, b. Epithelial overgrowth, c, Cross section of 

 epithelial downgrowth, showing central degeneration, d, d, d, Capillary 

 dilatation in (Edematous corium. e, Portion enlarged in PI. IT, fig. 3. 



Plate II. 



Fig. 3. Portion of fig. 2 enlarged. Magnification, 415 X 1. a, Beginning degener- 

 ation of epithelium. 6, 6, b, Capillary dilatation. 



Plate III. 



Fig. 4. Cross section through an epithelial downgrowth from an older nodule 

 from a monkey, showing the necrosis of the central cells with preserva- 

 tion of younger cells at the margins. The oedema of the cutis also is 

 well indicated. Magnification, 520 X 1. 



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