﻿ETIOLOGY OF MYCETOMA. 501 



The only important data tending to show that different types of the 

 disease exist are found in the varying color of the granules from the 

 different varieties and the results of Wright's cultivation experiments. 

 While Wright could not establish the etiologic importance of his or- 

 ganism, it is probable that it was the cause of the disease in his case; 

 this being true, the etiologic identity of the two varieties must be 

 questioned until further experimental work is done with both Wright's 

 and our own organisms. 



One of our experiments on monkeys is suggestive. A fair number 

 of small, black granules were produced in the tissues of monkey number 

 3267 inoculated subcutaneously, and a less decided, but positive, varia- 

 tion in the color of the granules has been noticed in other inoculated 

 animals. 



The statement which has often been repeated, that the ochroid variety 

 of mycetoma is actinomycosis, is not supported by the weight of evidence 

 in the literature, and it is positively disproved by our work. 



There is no doubt but that actinomycosis has been mistaken for 

 Madura foot, both of the ochroid - and black variety, in some of the 

 reported cases, but it is equally certain that Actinomyces hominis is a 

 different species of Strepiothrix from those producing mycetoma. 

 Furthermore, the two diseases show decided differences in clinical mani- 

 festations and in the pathologic findings. 



BIBLIOGRAPHY. 



[Edited by Miss Mary Polk, Librarian, Bureau of Science.] 



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 Further observations upon Madura foot disease in America. Montreal Med. 



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 Agnew, D. H. Mycetoma of India. In his: Principles and practice of surgery, 



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 Albertini, Antonio Diaz. See Desvernine, Albertini, Calnek, Debayle, and 



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dos casos de pie de Madura. Rev. de med. trop., Havana (1901), 2, 73-87. 

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Ztschr. f. Hyg. u. Infectionskrankh., Leipz. (1890), 8, 189-198, 1 pi. 

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